Serum extracellular vesicles contain protein biomarkers for primary sclerosing cholangitis and cholangiocarcinoma

Ander Arbelaiz, Mikel Azkargorta, Marcin Krawczyk, Alvaro Santos‐Laso, Ainhoa Lapitz, Maria J. Perugorria, Oihane Erice, Esperanza Gonzalez, Raul Jimenez‐Agüero, Adelaida Lacasta, Cesar Ibarra, Alberto Sanchez‐Campos, Juan P. Jimeno, Frank Lammert, Piotr Milkiewicz, Marco Marzioni, Rocio I.R. Macias, Jose J.G. Marin, Tushar Patel, Gregory J. Gores, Ibon Martinez, Félix Elortza, Juan M. Falcon‐Perez, Luis Bujanda, Jesus M. Banales – 26 May 2017 – Cholangiocarcinoma (CCA) includes a heterogeneous group of biliary cancers with poor prognosis.

Stratifying risk in the prevention of recurrent variceal hemorrhage: Results of an individual patient meta‐analysis

Agustín Albillos, Javier Zamora, Javier Martínez, David Arroyo, Irfan Ahmad, Joaquin De‐la‐Peña, Juan‐Carlos Garcia‐Pagán, Gin‐Ho Lo, Shiv Sarin, Barjesh Sharma, Juan G. Abraldes, Jaime Bosch, Guadalupe Garcia‐Tsao, on behalf of the Baveno Cooperation – 25 May 2017 – Endoscopic variceal ligation plus beta‐blockers (EVL+BB) is currently recommended for variceal rebleeding prophylaxis, a recommendation that extends to all patients with cirrhosis with previous variceal bleeding irrespective of prognostic stage.

Plasma cystatin C is a predictor of renal dysfunction, acute‐on‐chronic liver failure, and mortality in patients with acutely decompensated liver cirrhosis

Daniel Markwardt, Lesca Holdt, Christian Steib, Andreas Benesic, Flemming Bendtsen, Mauro Bernardi, Richard Moreau, Daniel Teupser, Julia Wendon, Frederik Nevens, Jonel Trebicka, Elisabet Garcia, Marco Pavesi, Vicente Arroyo, Alexander L. Gerbes – 25 May 2017 – The development of acute‐on‐chronic liver failure (ACLF) in patients with liver cirrhosis is associated with high mortality rates. Renal failure is the most significant organ dysfunction that occurs in ACLF. So far there are no biomarkers predicting ACLF.

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Omair Atiq, Jasmin Tiro, Adam C. Yopp, Adam Muffler, Jorge A. Marrero, Neehar D. Parikh, Caitlin Murphy, Katharine McCallister, Amit G. Singal – 24 May 2017

FIB‐4 stage of liver fibrosis predicts incident heart failure among HIV‐infected and uninfected patients

Kaku A. So‐Armah, Joseph K. Lim, Vincent Lo Re, Janet P. Tate, Chung‐Chou H. Chang, Adeel A. Butt, Cynthia L. Gibert, David Rimland, Vincent C. Marconi, Matthew B. Goetz, Maria C. Rodriguez‐Barradas, Matthew J. Budoff, Hilary A. Tindle, Jeffrey H. Samet, Amy C. Justice, Matthew S. Freiberg, for the Veterans Aging Cohort Study Project Team – 24 May 2017 – Liver fibrosis is common, particularly in individuals who are infected with human immunodeficiency virus (HIV). HIV‐infected individuals have excess congestive heart failure (CHF) risk compared with uninfected people.

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