Stéphanie Roullet, Geneviève Freyburger, Maximilien Cruc, Alice Quinart, Laurent Stecken, Magali Audy, Laurence Chiche, François Sztark – 20 October 2014 – Orthotopic liver transplantation (OLT) remains a potentially hemorrhagic procedure. Rotational thromboelastometry (ROTEM) is a point‐of‐care device used to monitor coagulation during OLT. Whether it allows blood loss and transfusions to be reduced during OLT remains controversial. Excellent correlations and predictive values have been found between ROTEM parameters and fibrinogen.

Marie‐Louise Lindberg Pind, Søren Møller, Nasrin Faqir, Flemming Bendtsen – 20 October 2014

Eric Lawitz, Fred Poordad, Diana M. Brainard, Robert H. Hyland, Di An, Hadas Dvory‐Sobol, William T. Symonds, John G. McHutchison, Fernando E. Membreno – 16 October 2014 – Sofosbuvir (SOF) in combination with ribavirin (RBV) for 12 or 24 weeks is the current standard of care for patients infected with hepatitis C virus (HCV) genotypes 2 and 3, respectively. However, in clinical trials treatment‐experienced patients, particularly those with cirrhosis, had suboptimal sustained virological response (SVR) rates.

Eric Lawitz, Fred Poordad, Diana M. Brainard, Robert H. Hyland, Di An, Hadas Dvory‐Sobol, William T. Symonds, John G. McHutchison, Fernando E. Membreno – 16 October 2014 – Sofosbuvir (SOF) in combination with ribavirin (RBV) for 12 or 24 weeks is the current standard of care for patients infected with hepatitis C virus (HCV) genotypes 2 and 3, respectively. However, in clinical trials treatment‐experienced patients, particularly those with cirrhosis, had suboptimal sustained virological response (SVR) rates.

Michael Abecassis – 14 October 2014

Eric M. Yoshida, Mark S. Sulkowski, Edward J. Gane, Robert W. Herring, Vlad Ratziu, Xiao Ding, Jing Wang, Shu‐Min Chuang, Julie Ma, John McNally, Luisa M. Stamm, Diana M. Brainard, William T. Symonds, John G. McHutchison, Kimberly L. Beavers, Ira M. Jacobson, K.

Eric M. Yoshida, Mark S. Sulkowski, Edward J. Gane, Robert W. Herring, Vlad Ratziu, Xiao Ding, Jing Wang, Shu‐Min Chuang, Julie Ma, John McNally, Luisa M. Stamm, Diana M. Brainard, William T. Symonds, John G. McHutchison, Kimberly L. Beavers, Ira M. Jacobson, K.

Marina Serper, Rachel E. Patzer, Peter P. Reese, Kamila Przytula, Rachel Koval, Daniela P. Ladner, Josh Levitsky, Michael M. Abecassis, Michael S. Wolf – 13 October 2014 – Medication nonadherence after liver transplantation (LT) is associated with adverse clinical outcomes such as graft rejection and graft loss. Few studies have examined nonadherence and its impact on clinical outcomes in LT.

Michael J. J. Chu, Anthony J. R. Hickey, Yannan Jiang, Amorita Petzer, Adam S. J. R. Bartlett, Anthony R. J. Phillips – 13 October 2014 – Steatotic livers are susceptible to cold ischemia, which is thought to be secondary to mitochondrial dysfunction. Ischemic preconditioning (IPC) has been reported to improve liver function in the setting of warm ischemia/reperfusion injury, but the effect of IPC on steatotic liver mitochondrial function (MF) with cold ischemia has not been previously evaluated.

Ryo Hatano, Kaori Akiyama, Atsushi Tamura, Shigekuni Hosogi, Yoshinori Marunaka, Michael J. Caplan, Yoshiyuki Ueno, Sachiko Tsukita, Shinji Asano – 13 October 2014 – Cholangiopathies share common features, including bile duct proliferation, periportal fibrosis, and intrahepatic cholestasis. Damage of biliary epithelium by autoimunne disorder, virus infection, toxic compounds, and developmental abnormalities causes severe progressive hepatic disorders responsible for high mortality.