Improvement in nonalcoholic fatty liver disease through bariatric surgery
Emily Truong, Mazen Noureddin – 21 July 2022
Bile acid conjugation deficiency causes hypercholanemia, hyperphagia, islet dysfunction, and gut dysbiosis in mice
Bandar D. Alrehaili, Mikang Lee, Shogo Takahashi, Robert Novak, Bipin Rimal, Shannon Boehme, Samuel A. J. Trammell, Trisha J. Grevengoed, Devendra Kumar, Yazen Alnouti, Katya Chiti, Xinwen Wang, Andrew D. Patterson, John Y. L. Chiang, Frank J. Gonzalez, Yoon‐Kwang Lee – 21 July 2022 – Bile acid‐CoA: amino acid N‐acyltransferase (BAAT) catalyzes bile acid conjugation, the last step in bile acid synthesis. BAAT gene mutation in humans results in hypercholanemia, growth retardation, and fat‐soluble vitamin insufficiency.
Pneumocystis jiroveci pneumonia prophylaxis in patients with autoimmune hepatitis
Patrick Stauffer, Joseph Ahn – 21 July 2022
Rhesus rotavirus receptor‐binding site affects high mobility group box 1 release, altering the pathogenesis of experimental biliary atresia
Sujit K. Mohanty, Bryan Donnelly, Haley Temple, Sarah Mowery, Holly M. Poling, Jaroslaw Meller, Astha Malik, Monica McNeal, Greg Tiao – 21 July 2022 – Biliary atresia (BA) is a neonatal inflammatory cholangiopathy that requires surgical intervention by Kasai portoenterostomy to restore biliary drainage. Even with successful portoenterostomy, most patients diagnosed with BA progress to end‐stage liver disease, necessitating a liver transplantation for survival.
CON: Should patients with nonalcoholic steatohepatitis fibrosis undergo bariatric surgery as a primary treatment?
Eric B. Newton, Jason Pan, Waihong Chung – 21 July 2022
Emerging liquid biopsy techniques for early detection of hepatocellular carcinoma, prognostication, and disease monitoring
Ashwini Arvind, Amit G. Singal – 21 July 2022
Overview of autoimmune liver disease: Prevalence, risk factors, and role of autoantibodies
Dong Xi, Henry Lin, Amit A. Shah – 21 July 2022
Diagnosis and management of hepatic encephalopathy: A summary for patients
Ellen W. Green, Arnab Mitra – 21 July 2022
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Laurens A. Kleef, Milan J. Sonneveld, Robert J. Knegt – 20 July 2022
Acute hepatitis of unknown origin in children: Behind the statistics
Randa Elsheikh, Hoang Thuy Tien, Abdelrahman M. Makram, Nguyen Thanh Van, Trang Thi Bich Le, Tamilarasy Vasanthakumaran, Nguyen Tien Huy – 20 July 2022 – Since April 2022, the world has been witnessing a rapidly spreading outbreak of acute hepatitis of unknown origin in children < 16 years old that has affected several countries around the world. Most of the cases have presented with the clinical picture of severe hepatitis that has led to resorting to liver transplantation in several cases.