Feng Liu, Zhi‐Da Liu, Nan Wu, Xu Cong, Ran Fei, Hong‐Song Chen, Lai Wei – 28 August 2009 – Cirrhosis is the most common end stage of liver diseases, and there are no effective treatment methods. Here we evaluated the effect of endothelial progenitor cell (EPC) transplantation from rat bone marrow (BM) on the development of cirrhosis induced by carbon tetrachloride (CCl4). Ex vivo generated, characterized, and cultivated rat BM–derived EPCs were identified by their vasculogenic properties in vitro.

Hiroyuki Sugimoto, Koichi Kato, Masashi Hirota, Shin Takeda, Hideya Kamei, Taro Nakamura, Tetsuya Kiuchi, Akimasa Nakao – 28 August 2009 – To elucidate the role of Doppler hepatic hemodynamic parameters as surrogate markers of acute rejection (AR) after live donor liver transplantation (LDLT), serial Doppler measurements were prospectively performed during the first 2 weeks after LDLT to compare the longitudinal hepatic hemodynamic changes between patients with histologically proven AR and patients without histologically proven AR.

Er‐Jiao Xu, Ren Mao, Rong‐Qin Zheng, Min‐Qiang Lu, Mei Liao, Jie Ren, Kai Li – 28 August 2009

Charles D. Howell – 28 August 2009

Justin D. Ellett, Zachary P. Evans, Carl Atkinson, Michael G. Schmidt, Rick G. Schnellmann, Kenneth D. Chavin – 28 August 2009 – Steatotic donors are routinely rejected for transplantation because of their increased rate of primary nonfunction. These grafts are more sensitive to ischemia/reperfusion (I/R) during transplantation. Removal of endotoxin before reperfusion improves liver performance post‐I/R. We hypothesize that the main modality of injury in steatotic livers is toll‐like receptor 4 (TLR4) signaling.

Alexander J. C. IJtsma, Christian S. van der Hilst, Marieke T. de Boer, Koert P. de Jong, Paul M. J. G. Peeters, Robert J. Porte, Maarten J. H. Slooff – 28 August 2009 – This study assesses the relation between the anhepatic phase duration and the outcome after liver transplantation. Of 645 patients who underwent transplantation between 1994 and 2006, 194 were recipients of consecutive adult primary piggyback liver transplants using heart‐beating donors. The anhepatic phase was defined as the time from the physical removal of the liver from the recipient to recirculation of the graft.

Karen L. Krok, Farida Milwalla, Anurag Maheshwari, Rebecca Rankin, Paul J. Thuluvath – 28 August 2009 – Cardiovascular (CV) disease has a significant impact on post–liver transplantation (LT) survival. Finding surrogate markers for occult CV disease would improve CV assessment in the LT evaluation. This study was designed to determine the prevalence of microvascular disease (MVD) and the utility of both microalbuminuria and the homeostatic model for insulin resistance (HOMA‐IR) for assessing the presence of MVD in potential LT recipients.

Svetlana Karie‐Guigues, Nicolas Janus, Faouzi Saliba, Jerome Dumortier, Christophe Duvoux, Yvon Calmus, Richard Lorho, Gilbert Deray, Vincent Launay‐Vacher, Georges‐Philippe Pageaux – 28 August 2009 – The prevalence of renal insufficiency before and at 1, 12, and 60 months after liver transplantation (LTx; primary endpoint) and the changes in the glomerular filtration rate (GFR) at same time points according to the immunosuppressive regimen (coprimary endpoint) were investigated.

James D. Perkins – 28 August 2009

Phillip S. Pang, Ahmad Kamal, Jeffrey S. Glenn – 28 August 2009 – The purpose of this study was to determine the effect of donor race on the outcome of black patients with chronic hepatitis C infection who undergo liver transplantation. The records for deceased donor liver transplants that occurred in the United States between January 1998 and December 2007 were obtained from the United Network for Organ Sharing. 26,212 records contained sufficient data to be included in the analysis.