Acute graft‐versus‐host disease after liver transplant: Novel use of etanercept and the role of tumor necrosis factor α inhibitors
Lena Thin, Gerry MacQuillan, Leon Adams, George Garas, Cynthia Seow, Paul Cannell, Bradley Augustson, Andrew Mitchell, Luc Delriveire, Gary Jeffrey – 26 March 2009 – Acute graft‐versus‐host disease following orthotopic liver transplantation is a rare but feared complication arising in 1% to 2% of cases with a dismal prognosis. It most often presents as fever, rash, and diarrhea with or without pancytopenia. Patients die from complications of marrow failure such as sepsis or bleeding. Because of its low incidence, there is no clear treatment protocol for this complication.