Effect of ischemic preconditioning on the genomic response to reperfusion injury in deceased donor liver transplantation
Wayel Jassem, Susan Fuggle, Richard Thompson, Matthew Arno, Jennifer Taylor, Jane Byrne, Nigel Heaton, Mohamed Rela – 24 November 2009 – Ischemic preconditioning (IP) is an effective method for protecting organs from ischemia/reperfusion (IR) injury; however, the molecular basis of this protective effect is poorly understood. This study assessed the gene expression profile in liver allografts during transplantation and evaluated the impact of IP.