Virology and pathogenesis of hepatitis C virus recurrence
Santseharay Ramírez, Sofía Pérez‐del‐Pulgar, Xavier Forns – 29 September 2008
Temporary portocaval shunt in orthotopic liver transplantation: Need for a standardized approach?
Diego Davila, Adam Bartlett, Nigel Heaton – 29 September 2008 – Maintenance of portal and systemic venous return during the anhepatic phase of liver transplantation (LT) improves hemodynamic stability. With the piggyback technique, caval return is maintained; however, temporary clamping of the portal vein is still necessary. The use of a temporary portocaval shunt (TPCS) has been proposed to minimize the effect of portal venous interruption.
Management of patients with decompensated hepatitis B virus associated cirrhosis
Fabien Zoulim, Sylvie Radenne, Christian Ducerf – 29 September 2008
Patient Transplant Survival Not Influenced by Type of Liver Graft
James D. Perkins – 29 September 2008
Impact of the hepatitis B virus genotype on pre– and post–liver transplantation outcomes
Paul Gaglio, Sundeep Singh, Bulent Degertekin, Michael Ishitani, Munira Hussain, Robert Perrillo, Anna S. Lok – 29 September 2008 – Emerging data suggest that the hepatitis B virus (HBV) genotype and the precore and core promoter variants impact the outcome of orthotopic liver transplantation (OLT) for hepatitis B. The aim of this study was to determine if there is a correlation between HBV genotype, precore and core promoter variants, and pre‐ and post‐OLT outcomes.
How to diagnose and treat hepatitis B virus antiviral drug resistance in the liver transplant setting
Anna S. F. Lok – 29 September 2008
Prevention and management of brain edema in patients with acute liver failure
Fin Stolze Larsen, Julia Wendon – 29 September 2008
Hepatocellular cancer arises from loss of transforming growth factor beta signaling adaptor protein embryonic liver fodrin through abnormal angiogenesis
Hye Jung Baek, Sung Chul Lim, Krit Kitisin, Wilma Jogunoori, Yi Tang, M. Blair Marshall, Bibhuti Mishra, Tae Hyun Kim, Kwan Ho Cho, Sang Soo Kim, Lopa Mishra – 26 September 2008 – We have previously demonstrated that 40%‐70% of elf+/− mice spontaneously develop hepatocellular cancer (HCC) within 15 months, revealing the importance of the transforming growth factor‐beta (TGF‐β) signaling pathway in suppressing tumorigenesis in the liver.
Virion half‐life in chronic hepatitis B infection is strongly correlated with levels of viremia
Maura Dandri, John M. Murray, Marc Lutgehetmann, Tassilo Volz, Ansgar W. Lohse, Joerg Petersen – 26 September 2008 – Analysis of hepatitis B virus (HBV) kinetics with mathematical models may disclose new aspects of HBV infection and host response mechanisms.
Altered hepatic triglyceride content after partial hepatectomy without impaired liver regeneration in multiple murine genetic models
Elizabeth P. Newberry, Susan M. Kennedy, Yan Xie, Jianyang Luo, Susan E. Stanley, Clay F. Semenkovich, Roseanne M. Crooke, Mark J. Graham, Nicholas O. Davidson – 26 September 2008 – Liver regeneration is impaired following partial hepatectomy (PH) in mice with genetic obesity and hepatic steatosis and also in wild‐type mice fed a high‐fat diet. These findings contrast with other data showing that liver regeneration is impaired in mice in which hepatic lipid accumulation is suppressed by either pharmacologic leptin administration or by disrupted glucocorticoid signaling.