Rapid evolution of congenital hepatic fibrosis after liver transplantation for acute liver failure: The potential role of extrahepatic factors

Judith Flores, Ronen Arnon, Raffaella A. Morotti, Lisa Guay‐Woodford, Sukru Emre, Benjamin L. Shneider – 23 April 2008 – A 9‐year‐old male underwent deceased donor liver transplantation for idiopathic fulminant hepatic failure. In the postoperative period, a review of perioperative biopsies of the donor liver revealed mild features of congenital hepatic fibrosis. Over the ensuing year, the recipient developed severe complications of congenital hepatic fibrosis including multiple episodes of cholangitis and progressive portal hypertension.

Safety and efficacy of the percutaneous treatment of bile leaks in hepaticojejunostomy or split‐liver transplantation without dilatation of the biliary tree

Dorico Righi, Alessandro Franchello, Alessandro Ricchiuti, Andrea Doriguzzi Breatta, Karine Versace, Amedeo Calvo, Renato Romagnoli, P. Fonio, Giovanni Gandini, Mauro Salizzoni – 23 April 2008 – Biliary leaks complicating hepaticojejunostomy (HJA) or fistulas from cut surface are severe complications after liver transplantation (LT) and split‐liver transplantation (SLT). The aim of the study was to describe our experience about the safety and efficacy of radiological percutaneous treatment without dilatation of intrahepatic biliary ducts.

Acute hypotensive transfusion reaction during liver transplantation in a patient on angiotensin converting enzyme inhibitors from low aminopeptidase P activity

Cataldo Doria, Elia S. Elia, Yoogoo Kang, Albert Adam, Anik Desormeaux, Carlo Ramirez, Adam Frank, Fabrizio di Francesco, Jay H. Herman – 23 April 2008 – Acute hypotensive transfusion reactions are newly characterized transfusion reactions in which hypotension is the prominent feature. The pathophysiology of acute hypotensive transfusion reactions is related to the bradykinin function and its metabolism.

Sirolimus in liver transplant recipients with renal dysfunction offers no advantage over low‐dose calcineurin inhibitor regimens

Derek DuBay, Rob J. Smith, Kenneth G. Qiu, Gary A. Levy, Leslie Lilly, George Therapondos – 23 April 2008 – The purpose of this study is to review the clinical experience with sirolimus immunosuppression in liver transplant patients with calcineurin inhibitor–induced chronic renal insufficiency. The study design is a case‐control retrospective series. Fifty‐seven liver transplant patients with renal insufficiency that were started on sirolimus at greater than 90 days postoperatively and treated for more than 90 days were identified.

Subscribe to