Yvonne Meier, Christiane Pauli‐Magnus, Ulrich M. Zanger, Kathrin Klein, Elke Schaeffeler, Andreas K. Nussler, Natascha Nussler, Michel Eichelbaum, Peter J. Meier, Bruno Stieger – 23 June 2006 – Interindividual variability in hepatic canalicular transporter expression might predispose to the development of hepatic disorders such as acquired forms of intrahepatic cholestasis.
Michael Kremer, Ian Neil Hines, Richard Jameson Milton, Michael Daryl Wheeler – 23 June 2006 – Steatohepatitis enhances the severity of liver injury caused by acute inflammation. The purpose of this study was to test the hypothesis that fatty liver due to chronic choline‐deficient diet exacerbates concanavalin A (ConA)‐induced liver hepatitis, which is predominantly facilitated by T cells. Male C57BL/6 mice were fed either control choline‐sufficient diet (CSD) or choline‐deficient diet (CDD) for 6 weeks before ConA administration.
Ronan E. O'Carroll, Lesley M. McGregor, Vivien Swanson, George Masterton, Peter C. Hayes – 13 June 2006 – This study assessed adherence to medication after liver transplantation and consisted of 2 components: a retrospective audit involving the examination of the Scottish national database, and a preliminary study assessing psychological factors implicated in poor adherence.
Mikiko Ueda, Fumitaka Oike, Yasuhiro Ogura, Kenji Uryuhara, Yasuhiro Fujimoto, Mureo Kasahara, Kohei Ogawa, Koichi Kozaki, Hironori Haga, Koichi Tanaka – 13 June 2006 – This report concerns the long‐term outcome of living donor liver transplantation (LDLT) for pediatric patients at a single center. Between June 1990 and December 2003, a total of 600 LDLTs, including 568 primary transplantations and 32 retransplantations, were performed for pediatric patients, who were immunosuppressed with FK506 and low‐dose corticosteroids.
Gabriele I. Kirchner, Kinan Rifai, Tobias Cantz, Bjoern Nashan, Christoph Terkamp, Thomas Becker, Christian Strassburg, Hannelore Barg‐Hock, Siegfried Wagner, Rainer Lück, Juergen Klempnauer, Michael P. Manns – 1 June 2006 – In advanced stages of polycystic liver disease, often associated with polycystic kidney disease, a curative therapy is liver or combined liver‐kidney transplantation. However, little is known about long‐term outcome and quality of life.
Hubert Hetz, Peter Faybik, Gabriela Berlakovich, Amir Baker, Andreas Bacher, Christopher Burghuber, Sigrid E. Sandner, Heinz Steltzer, Claus Georg Krenn – 1 June 2006 – Early allograft dysfunction (EAD) after orthotopic liver transplantation (OLT) causes marked morbidity and mortality. We conducted a prospective pilot study to assess the safety and efficacy of molecular adsorbent recirculating system (MARS) in treatment of EAD after OLT.
Jacob Alexander, Ajit P. Limaye, Cynthia W. Ko, Mary P. Bronner, Kris V. Kowdley – 1 June 2006 – Invasive fungal infection is a serious complication of orthotopic liver transplantation, but its risk factors remain incompletely defined. Iron overload has already been associated with increased risk of fungal infections, but it has not yet been assessed as a risk factor in liver transplantation. We retrospectively studied a cohort of 153 consecutive patients who underwent their first liver transplantation at a single center and who survived at least 7 days after transplantation.
Angelo Luca, Roberto Miraglia, Settimo Caruso, Mariapina Milazzo, Bruno Gidelli, Jaime Bosch – 1 June 2006 – The specific contribution of splenic blood inflow to portal hypertension in patients with cirrhosis is still unclear. In this study, we investigated this contribution by assessing the hemodynamic effects of transient splenic artery occlusion.
Jérôme Dumortier, Marie‐Claude Gagnieu, Janine Salandre, Olivier Guillaud, Philipe Guillem, Mustapha Adham, Olivier Boillot – 1 June 2006 – Gastrointestinal (GI) disorders are one of the main adverse events in patients treated by mycophenolic acid (MPA).
Surakit Pungpapong, Salvador Alvarez, Walter C. Hellinger, David J. Kramer, Darrin L. Willingham, Julio C. Mendez, Justin H. Nguyen, Winston R. Hewitt, Jaime Aranda‐Michel, Denise M. Harnois, Barry G. Rosser, Christopher B. Hughes, Hani P. Grewal, Raj Satyanarayana, Rolland C. Dickson, Jeffrey L. Steers, Andrew P. Keaveny – 1 June 2006 – Peritonitis occurring after liver transplantation (PLT) has been poorly characterized to date. The aims of this study were to define the incidence, risk factors, microbiology profiles, and outcome of nonlocalized PLT.