Anastomotic biliary strictures after liver transplantation: Causes and consequences

Robert C. Verdonk, Carlijn I. Buis, Robert J. Porte, Eric J. van der Jagt, Abraham J. Limburg, Aad P. van den Berg, Maarten J.H. Slooff, Paul M.J.G. Peeters, Koert P. de Jong, Jan H. Kleibeuker, Elizabeth B. Haagsma – 20 April 2006 – We retrospectively studied the prevalence, presentation, results of treatment, and graft and patient survival of grafts developing an anastomotic biliary stricture (AS) in 531 adult liver transplantations performed between 1979 and 2003. Clinical and laboratory information was obtained from the hospital files, and radiological studies were re‐evaluated.

Bactobilia after liver transplantation: Frequency and antibiotic susceptibility

Gunda Millonig, Thomas Buratti, Ivo W. Graziadei, Hubert Schwaighofer, Dorothea Orth, Raimund Margreiter, Wolfgang Vogel – 20 April 2006 – After liver transplantation (LT), bactobilia occurs frequently in patients, leading in some cases to cholangitis and biliary sepsis. The present study is the first to investigate bactobilia after LT, and it gives an overview of predisposing factors for bactobilia, the microbial spectrum in the bile of LT patients, and the antibiotic susceptibility.

Tacrolimus dose requirement in relation to donor and recipient ABCB1 and CYP3A5 gene polymorphisms in Chinese liver transplant patients

Wang Wei‐lin, Jin Jing, Zheng Shu‐sen, Wu Li‐hua, Liang Ting‐bo, Yu Song‐feng, Yan Sheng – 20 April 2006 – The aim of this study was to investigate whether the heterogeneity in tacrolimus dose requirement is associated with ABCB1 and CYP3A5 gene polymorphisms in Chinese liver transplant patients during the first month after transplantation. ABCB1 and CYP3A5 genotyping was performed using the polymerase chain reaction restriction sites polymorphism–based procedure in Chinese liver transplant recipients (n = 50) and their corresponding donors (n = 50).

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