The patient's perspective in hepatitis C
Robert J. Fontana, Ziad Kronfol – 25 March 2004
Factor V Leiden as a risk factor for cirrhosis in chronic hepatitis C
Armelle Poujol‐Robert, Pierre‐Yves Boëlle, Raoul Poupon, Annie Robert – 25 March 2004
Celecoxib‐induced apoptosis in rat cholangiocarcinoma cells mediated by Akt inactivation and Bax translocation
Zichen Zhang, Guan‐Hua Lai, Alphonse E. Sirica – 25 March 2004 – Recently, we demonstrated that the cyclooxygenase‐2 (COX‐2) inhibitor celecoxib acts to significantly suppress the growth of rat C611B cholangiocarcinoma (ChC) cells in vitro. To establish a molecular mechanism for this growth suppression, we investigated the effects of celecoxib on apoptotic signaling pathways in cultured rat C611B ChC cells.
A murine model of type 2 autoimmune hepatitis: Xenoimmunization with human antigens
Pascal Lapierre, Idriss Djilali‐Saiah, Susana Vitozzi, Fernando Alvarez – 25 March 2004 – Autoimmune hepatitis (AIH) is characterized by an immune‐mediated injury of the hepatic parenchyma of unknown pathogenesis. Type 2 AIH is identified by the presence of anti‐liver‐kidney microsomes type 1 (anti‐LKM1) and anti‐liver cytosol type 1 (anti‐LC1) autoantibodies. The current study shows that a murine model of AIH can be generated by DNA immunization against type 2 AIH self‐antigens (P450 2D6 and formiminotransferase‐cyclodeaminase).
Persistence of elevated aminotransferases in Wilson's disease despite adequate theraphy.
Raffaele Iorio, Mariangela D'Ambrosi, Matilde Marcellini, Christiana Barbera, Giuseppe Maggiore, Lucia Zancan, Raffaella Giacchino, Pietro Vajro, Maria Grazia Marazzi, Ruggiero Francavilla, Fabio Michielutti, Massimo Resti, Tullio Frediani, Maria Pastore, Angela Vegnente – 25 March 2004
Tamoxifen in treatment of primary biliary cirrhosis
Pietro Invernizzi, Domenico Alvaro, Andrea Crosignani, Eugenio Gaudio, Mauro Podda – 25 March 2004
HLA and cytokine gene polymorphisms are independently associated with responses to hepatitis B vaccination
Chengbin Wang, Jianming Tang, Wei Song, Elena Lobashevsky, Craig M. Wilson, Richard A. Kaslow – 25 March 2004 – Variable immune responses to hepatitis B virus (HBV) infection and recombinant HBV vaccines have been associated with polymorphisms in several genes within the human leukocyte antigen (HLA) complex.
What doesn't kill you makes you stronger: How hepatocytes survive prolonged cholestasis
Jacquelyn J. Maher – 25 March 2004
Integration of woodchuck hepatitis and N‐myc rearrangement determine size and histologic grade of hepatic tumors
James R. Jacob, Agnes Sterczer, Ilia A. Toshkov, Amy E. Yeager, Brent E. Korba, Paul J. Cote, Marie‐Annick Buendia, John L. Gerin, Bud C. Tennant – 25 March 2004 – Integrations of woodchuck hepatitis virus (WHV) DNA and rearrangements of the N‐myc 2 gene have been detected frequently in hepatocellular carcinoma (HCC) of Eastern woodchucks (Marmota monax) chronically infected with WHV.