Hee Chul Yu, Heecheon You, Ho Lee, Zhe‐Wu Jin, Jang Il Moon, Baik Hwan Cho – 20 May 2004 – The standard liver volume (LV) of a recipient is estimated in liver transplantation to determine the minimum LV necessary for the recipient. Simple linear formulas of LV estimation were developed for the Japanese and Caucasian populations. The present study examined the applicability of the reported formulas to the Korean population. Liver density (LD) was determined by analyzing 24 healthy livers.

Lei Guo, Xiao‐Kang Li, Shin Enosawa, Naoko Funeshima, Seiichi Suzuki, Hiromitsu Kimura, Yasuhiko Sugawara, Katsunari Tezuka, Masatoshi Makuuchi – 20 May 2004 – A member of the costimulatory molecule family, inducible costimulator (ICOS), is expressed on activated T cells and plays a critical role in their primary activation and cytokine production. ICOS is involved in different immune phenomena, such as Th1‐mediated autoimmune disease and graft rejection.

Michael Charlton – 20 May 2004

Tania A. Roskams, Neil D. Theise, Charles Balabaud, Govind Bhagat, Prithi S. Bhathal, Paulette Bioulac‐Sage, Elizabeth M. Brunt, James M. Crawford, Heather A. Crosby, Valeer Desmet, Milton J. Finegold, Stephen A. Geller, Annette S.H. Gouw, Prodromos Hytiroglou, A.S. Knisely, Masamichi Kojiro, Jay H. Lefkowitch, Yasuni Nakanuma, John K. Olynyk, Young Nyun Park, Bernard Portmann, Romil Saxena, Peter J. Scheuer, Alastair J. Strain, Swan N. Thung, Ian R. Wanless, A.

Emilia Ip, Geoff Farrell, Pauline Hall, Graham Robertson, Isabelle Leclercq – 26 April 2004 – Administration of a methionine and choline deficient (MCD) diet to rodents causes progressive fibrosing steatohepatitis pathologically similar to human metabolic steatohepatitis. We have previously shown that the peroxisome proliferator‐activated receptor‐α (PPARα) agonist, Wy‐14,643, prevented the development of MCD diet‐induced steatohepatitis. We have now tested whether Wy‐14,643 ameliorates established steatohepatitis and fibrosis.

Toshitaka Hoppo, Hideaki Fujii, Tetsuro Hirose, Kentaro Yasuchika, Hisaya Azuma, Shinji Baba, Masato Naito, Takafumi Machimoto, Iwao Ikai – 26 April 2004 – Previously, we reported a system to enrich mouse fetal hepatic progenitor cells (HPCs) by forming cell aggregates. In this study, we sorted two cell populations, CD49f+Thy1−CD45− cells (CD49f‐postive cells) and CD49f±Thy1+CD45− cells (Thy1‐positive cells), from the cell aggregates using a flow cytometer.

Hideyuki Nomura, Suketo Sou, Hironori Tanimoto, Takashi Nagahama, Yoichi Kimura, Jun Hayashi, Hiromi Ishibashi, Seizaburo Kashiwagi – 26 April 2004 – Acute hepatitis C often progresses to chronic infection. We undertook a randomized controlled trial to determine whether short‐term therapy with interferon (IFN) during acute hepatitis C is effective in preventing the development of chronic hepatitis. Thirty patients with acute hepatitis C were randomized into 1 of 2 treatment groups.

Archana Sud, Jason M. Hui, Geoffrey C. Farrell, Priyanka Bandara, James G. Kench, Carolyn Fung, Rita Lin, Dev Samarasinghe, Christopher Liddle, Geoffrey W. McCaughan, Jacob George – 26 April 2004 – We sought to develop a clinically useful index comprising standard and physiologically relevant variables to predict the probability of significant hepatic fibrosis in subjects with chronic hepatitis C virus (HCV) infection. Fibrosis was graded as mild (stages F0 or F1) or significant (stages F2–F4).

Steven F. Solga, Anna Mae Diehl – 26 April 2004

Thomas Berg, Christoph Sarrazin, Holger Hinrichsen, Peter Buggisch, Tilman Gerlach, Reinhart Zachoval, Stefan Zeuzem – 26 April 2004