Tailoring donor hepatectomy per segment 4 venous drainage in right lobe live donor liver transplantation

See Ching Chan, Chung Mau Lo, Chi Leung Liu, Yik Wong, Sheung Tat Fan, John Wong – 20 May 2004 – Including the middle hepatic vein (MHV) in the right lobe liver graft for adult‐to‐adult live donor liver transplantation provides more functional liver by securing adequate venous drainage. Donor outcome of this procedure in relation to different venous drainage patterns of segment 4 is unknown. Modification of graft harvesting technique by preserving segment 4b hepatic vein (V4b) in theory compensates for unfavorable venous drainage patterns.

The effect of donor weight reduction on hepatic steatosis for living donor liver transplantation

Shin Hwang, Sung‐Gyu Lee, Se‐Jin Jang, Sung‐Hun Cho, Ki‐Hun Kim, Chul‐Soo Ahn, Deok‐Bog Moon, Tae‐Yong Ha – 20 May 2004 – Hepatic steatosis is often associated with overweight, so we tried body‐weight reduction in potential living donors with fatty liver and/or obesity to alleviate hepatic steatosis. We advised to reducing the body weight by 5% for 9 potential living donors showing hepatic steatosis of 25–95% on initial percutaneous needle biopsy (PCNB). They lost 5.9 ± 2.0% of the initial body weight during 2–6 months and their body mass index changed from 25.3 ± 3.8 to 23.7 ± 3.4.

Cytotoxic T‐cell elimination during anti‐CD4–induced rat liver acceptance and rapid replacement of functional graft antigen–presenting cells

Kazuhiro Usui, Junzo Yamaguchi, Weili Gu, Takashi Kanematsu – 20 May 2004 – In previous studies, we showed that primed T cells were eliminated in long‐term survival Wistar Furth (WF) recipient rats with spontaneously accepted Lewis (LEW) liver graft and that the grafted liver lost the ability to elicit rejection reaction early after liver transplantation. We hypothesized that the same phenomenon may be observed in tolerant animals after immunosuppression in a rejector rat strain combination (WF→LEW).

Advances in adult living donor liver transplantation: A review based on reports from the 10th anniversary of the adult‐to‐adult living donor liver transplantation meeting in Tokyo

Yasuhiko Sugawara, Masatoshi Makuuchi – 20 May 2004 – In 1993, the Shinshu Group performed the first successful adult‐to‐adult living donor liver transplantation (LDLT). During the first 10 years of LDLT, many technical innovations have been reported. The major limitation of LDLT for adult recipients is the size of the graft. To overcome the problem, several graft types were designed, including left liver graft with caudate lobe, right liver, modified right liver, and right lateral sector and dual grafts.

Nomenclature of the finer branches of the biliary tree: Canals, ductules, and ductular reactions in human livers

Tania A. Roskams, Neil D. Theise, Charles Balabaud, Govind Bhagat, Prithi S. Bhathal, Paulette Bioulac‐Sage, Elizabeth M. Brunt, James M. Crawford, Heather A. Crosby, Valeer Desmet, Milton J. Finegold, Stephen A. Geller, Annette S.H. Gouw, Prodromos Hytiroglou, A.S. Knisely, Masamichi Kojiro, Jay H. Lefkowitch, Yasuni Nakanuma, John K. Olynyk, Young Nyun Park, Bernard Portmann, Romil Saxena, Peter J. Scheuer, Alastair J. Strain, Swan N. Thung, Ian R. Wanless, A.

Screening in liver disease: Report of an AASLD clinical workshop

Paul C. Adams, Michael J. Arthur, Thomas D. Boyer, Laurie D. DeLeve, Adrian M. Di Bisceglie, Mark Hall, Theodore R. Levin, Dawn Provenzale, Leonard Seeff – 26 April 2004 – This report summarizes an AASLD Clinical Workshop that was presented at Digestive Diseases Week 2003 on screening in liver diseases. As newer diagnostic tests become available, many liver diseases and complications of liver disease can be detected at an early asymptomatic stage. In many cases, early detection can lead to earlier treatment and an improved outcome.

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