Silvio Balzan, Olivier Farges, Daniele Sommacale, Federica Dondero, Maryléne Plasse, Jacques Belghiti – 20 April 2004 – The split‐liver technique is an important means to alleviating donor shortage. Its development is, at least in part, hindered by the risk of biliary complications, particularly when splitting is performed ex situ. We present a simple technique aimed at improving the identification of the biliary anatomy at the hilar level and the safety of the procedure. (Liver Transpl 2004;10:703–705.)

Giuliano La Barba, Marco Vivarelli, Rita Golfieri, Maria Rosa Tamè, Mauro Caputo, Fabio Piscaglia, Antonino Cavallari – 20 April 2004

Abhinav Humar, Khalid Khwaja, Brooke Glessing, Elizabeth Larson, Massimo Asolati, Brenda Durand, John Lake, William D. Payne – 20 April 2004 – On August 21, 1999, Region 7 of the United Network for Organ Sharing (UNOS) adopted a policy of regionwide sharing of cadaver livers for UNOS Status 1 recipients. We examined what impact this policy had at our center on their waiting times, waiting list mortality, and outcomes.

Raoul Poupon – 25 March 2004

Adrian Reuben – 25 March 2004

Naoya Yahagi, Motohiro Sekiya, Hitoshi Shimano – 25 March 2004

Geeta Upadhyay, Rajesh Singh, Ashok Kumar, Sanjeev Kumar, Amit Kapoor, Madan M. Godbole – 25 March 2004 – Thyrotoxicosis may be associated with a variety of abnormalities of liver function. The pathogenesis of hepatic dysfunction in thyrotoxicosis is unknown, but has been attributed to mitochondrial dysfunction. We studied the effect of altered thyroid function on the apoptotic index in rat liver.

Bin Gao, Feng Hong, Svetlana Radaeva – 25 March 2004 – Failure of interferon‐α (IFN‐α) treatment in patients with chronic hepatitis C virus (HCV) infection is a challenging obstacle for clinical and experimental hepatology. Both viral and host factors have been implicated in reducing responsiveness to IFN‐α therapy. The role of viral factors has been studied extensively and has been summarized in several review articles; however, much less attention has been paid to host factors. In this paper, we review evidence of host factor involvement in IFN‐α treatment failure.

Henar Hevia, Marta Varela‐Rey, Fernando J. Corrales, Carmen Berasain, María L. Martínez‐Chantar, M. Ujue Latasa, Shelly C. Lu, José M. Mato, Elena R. García‐Trevijano, Matías A. Avila – 25 March 2004 – 5′‐methylthioadenosine (MTA) is a nucleoside generated from S‐adenosylmethionine (AdoMet) during polyamine synthesis. Recent evidence indicates that AdoMet modulates in vivo the production of inflammatory mediators.

Christoph Köhler, Aaron W. Bell, William C. Bowen, Satdarshan P. Monga, Wolfgang Fleig, George K. Michalopoulos – 25 March 2004 – The Notch/Jagged signaling pathway is important for cellular differentiation and proliferation. Its dysfunction is associated with human pathologies in several tissues including liver. Point mutations in Jagged‐1 gene are the cause for Alagille syndrome, associated with paucity of intrahepatic bile ducts.