Heikki Makisalo, Anu Koivusalo, Anne Vakkuri, Krister Hockerstedt – 29 June 2004 – Liver transplantation (LT) may be indicated in cirrhotic patients with underlying pulmonary artery hypertension. However, severe pulmonary artery hypertension with mean pulmonary artery pressure (mPAP) above 50 mmHg has even been considered a contraindication to LT. We present a cirrhotic patient with an mPAP of 56 mmHg measured using right heart catheterization (RHC) and with severely compromised physical capacity.

Nina Singh, Marilyn M. Wagener, Asia Obman, Thomas V. Cacciarelli, Michael E. de Vera, Timothy Gayowski – 29 June 2004 – During the 1990s, gram‐positive bacteria emerged as major pathogens after liver transplantation. We sought to determine whether the pathogens associated with bacteremias in liver transplant recipients have changed. Patients included 233 liver transplant recipients transplanted between 1989 and 2003. The proportion of all infections due to bacteremias increased significantly over time (P < .0001).

Nathalie Stojeba, Carole Meyer, Catherine Jeanpierre, Frédéric Perrot, Christine Hirth, Thierry Pottecher, Jean‐Charles Deybach – 29 June 2004 – The porphyrias are a group of inherited or acquired enzymatic defects of heme biosynthesis. Each type of porphyria has a characteristic pattern of overproduction and accumulation of heme precursors based on the location of dysfunctional enzyme in the heme synthetic pathway.

James Neuberger – 29 June 2004

Mathew Jacob, Lynn P. Copley, James D. Lewsey, Alex Gimson, Giles J. Toogood, Mohamed Rela, Jan H. P. van der Meulen – 29 June 2004 – It has been shown that the model for end‐stage liver disease (MELD) score is an accurate predictor of survival in patients with liver disease without transplantation. Four recent studies carried out in the United States have demonstrated that the MELD score obtained immediately prior to transplantation is also associated with post‐transplant patient survival.

Guy W. Neff, Christopher O'Brien, Marzia Montalbano, Antoinette DeManno, Stephanie Kahn, Kamran Safdar, Seigo Nishida, Andreas Tzakis – 29 June 2004 – The extensive use of alternative medicine products, herbal remedies, and vitamins in large doses has reached an all time high in the general public. Some agents are reported and advertised as immune stimulants and may interfere with patients suffering from immune modification, autoimmune diseases, or transplant recipients.

Ruud A.F. Krom – 29 June 2004

Christian V. Hulzebos, Charles M.A. Bijleveld, Frans Stellaard, Folkert Kuipers, Vaclav Fidler, Maarten J.H. Slooff, Paul M.J.G. Peeters, Pieter J.J. Sauer, Henkjan J. Verkade – 29 June 2004 – Hyperlipidemia is a common side effect of cyclosporine A (CsA) after solid organ transplantation. CsA also markedly reduces the synthesis rate of bile salts in rats and can inhibit biliary bile salt secretion. It is not known, however, whether CsA inhibits the synthesis of bile salts in humans, and whether the hyperlipidemic effects of CsA are related to bile salt metabolism.

Francis Y. Yao, John P. Roberts – 29 June 2004

Didier Samuel – 29 June 2004