Ziv Ben‐Ari – 30 August 2004

Mohammed S. Khuroo, Mehnaaz S. Khuroo, Karim L.C. Farahat – 30 August 2004 – Molecular adsorbent recirculating system (MARS) is an important option for patients with liver failure to give them additional time for recovery or to serve as a “bridge” to transplantation. However, its effect on survival for such patients is not well known. Our aim was to assess the treatment effects of MARS on patients with acute and acute‐on‐chronic liver failure. The outcomes measure evaluated was survival.

Konrad L. Streetz, Torsten Wuestefeld, Michael P. Manns, Christian Trautwein – 30 August 2004

Lennox J. Jeffers, William Cassidy, Charles D. Howell, Sylvia Hu, K. Rajender Reddy – 30 August 2004

Masao Omata – 30 August 2004

Montserrat Garcia‐Retortillo, Xavier Forns, Josep M. Llovet, Miquel Navasa, Anna Feliu, Anna Massaguer, Miquel Bruguera, Josep Fuster, Juan Carlos Garcia‐Valdecasas, Antoni Rimola – 30 August 2004 – Preliminary reports suggested that hepatitis C virus (HCV) infection has a more aggressive course following living donor liver transplantation (LDLT) compared to cadaveric liver transplantation (CLT). The aim of this prospective study was to establish if HCV disease recurrence differs between LDLT and CLT.

Nicolas Carbonell, Arnaud Pauwels, Lawrence Serfaty, Olivier Fourdan, Victor George Lévy, Raoul Poupon – 30 August 2004 – Over the past two decades, new treatment modalities have been introduced for the management of variceal bleeding. The aim of this retrospective study in a single center was to assess whether these treatments have improved the prognosis for cirrhotic patients with variceal bleeding. We reviewed the clinical records of all patients with cirrhosis admitted to our Liver Intensive Care Unit due to variceal bleeding during the years 1980, 1985, 1990, 1995, and 2000.

Aparna Venkatraman, Sruti Shiva, Amanda Wigley, Elena Ulasova, David Chhieng, Shannon M. Bailey, Victor M. Darley‐Usmar – 30 August 2004 – Nitric oxide (NO) is now known to control both mitochondrial respiration and organelle biogenesis. Under conditions of ethanol‐dependent hepatic dysfunction, steatosis is increased, and this is associated with increased expression of inducible nitric oxide synthase (iNOS).

Xian Liang Li, Kwan Man, Kevin T. Ng, Terence K. Lee, Chung Mau Lo, Sheung Tat Fan – 30 August 2004 – Ischemia / reperfusion (I / R) injury is related to tissue graft energy status. Insulin, which is currently used in the University of Wisconsin (UW) preservation solution with insulin (UWI), is an anabolic hormone and was shown to exacerbate the hepatic I / R injury in our previous study. In this study, the energy status and regulation of metabolism genes by insulin were investigated in liver grafts preserved by UW solution.

Sambit Sen, Nathan A. Davies, Rajeshwar P. Mookerjee, Lisa M. Cheshire, Stephen J. Hodges, Roger Williams, Rajiv Jalan – 30 August 2004 – The pathophysiological basis of acute‐on‐chronic liver failure (ACLF) is unclear but systemic inflammatory response is thought to be important. In patients with ACLF, the molecular adsorbents recirculating system (MARS) improves individual organ function, but the effect of MARS on the proposed mediators of systemic inflammatory response is unclear.