Methemoglobinemia associated with dapsone treatment in solid organ transplant recipients: A two‐case report and review
J S Plotkin, J F Buell, M J Njoku, S Wilson, P C Kuo, S T Bartlett, C Howell, L B Johnson – 30 December 2003 – Dapsone, a sulfone antibiotic, has been increasingly used in solid‐organ transplant recipients for the primary prevention of Pneumocystis carinii pneumonia, especially in patients with documented sulfa allergy. A known side effect of dapsone therapy, however, is methemoglobinemia, a condition leading to impaired tissue oxygen delivery.