Methemoglobinemia associated with dapsone treatment in solid organ transplant recipients: A two‐case report and review

J S Plotkin, J F Buell, M J Njoku, S Wilson, P C Kuo, S T Bartlett, C Howell, L B Johnson – 30 December 2003 – Dapsone, a sulfone antibiotic, has been increasingly used in solid‐organ transplant recipients for the primary prevention of Pneumocystis carinii pneumonia, especially in patients with documented sulfa allergy. A known side effect of dapsone therapy, however, is methemoglobinemia, a condition leading to impaired tissue oxygen delivery.

Lower body impedance for the evaluation of venovenous bypass flow

E Ejlersen, P Sode, C Skak, A Rasmussen, K Espersen, P Kirkegaard, N H Secher – 30 December 2003 – Inferior vena cava (IVC) clamping during liver transplantation causes venous congestion in the splanchnic and IVC beds. A venovenous bypass relieves congestion and improves cardiac output (CO), but the bypass flow required for adequate drainage of the vascular beds is controversial. In this study we evaluated the bypass flow necessary to compensate for the IVC clamping. Lower body impedance (BI) is inversely related to tissue fluid content and was used to reflect congestion.

Hepatic steatosis: A specific sign of hepatitis C reinfection after liver transplantation

Leonardo Baiocchi, Giuseppe Tisone, Gianpiero Palmieri, Maria Rapicetta, Franco Pisani, Giuseppe Orlando, Carlo Umberto Casciani, Mario Angelico – 30 December 2003 – Hepatitis C virus (HCV) infection is one of the major causes leading to orthotopic liver transplantation (OLT) worldwide. Although viral infection persists in almost all patients, the pathology of recurrent HCV infection after OLT is not well characterized.

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