Attenuation of the ethanol‐induced hepatic redox change after chronic alcohol consumption in baboons: Metabolic consequences in vivo and in vitro
Mikko P. Salaspuro, Spencer Shaw, Elizabeth Jayatilleke, William A. Ross, Charles S. Lieber – 1 January 1981 – Acute ethanol administration results in increased hepatic NADH/NAD+ ratio and inhibition of galactose elimination, tricarboxylic acid cycle activity, and fatty acid oxidation. To determine how this redox change is affected by chronic alcohol consumption and to assess the resulting metabolic consequences, we studied baboons which were fed alcohol as 50% of their total calories.