Uncoupling of biliary lipid from bile acid secretion by formyl‐ methionyl‐leucyl‐phenylalanine in the rat
K Mizuno, M Hoshino, T Hayakawa, H Yamada, T Nakazawa, T Inagaki, T Takeuchi, M Kunimatsu – 1 November 1996 – A neutrophil chemotactic factor N‐formyl‐methionyl‐leucyl‐phenylalanine (fMLP), produced by Escherichia coli under conditions of intestinal inflammation, is reported to circulate enterohepatically in the presence of experimental colitis, but its effect on bile secretion is unclear. Therefore, we investigated the effect of fMLP on bile secretion in a single‐pass isolated perfused rat liver system.