TGFβ‐induced FOXS1 controls epithelial–mesenchymal transition and predicts a poor prognosis in liver cancer

Kevin Bévant, Matthis Desoteux, Gaëlle Angenard, Raphaël Pineau, Stefano Caruso, Corentin Louis, Panagiotis Papoutsoglou, Laurent Sulpice, David Gilot, Jessica Zucman‐Rossi, Cédric Coulouarn – 25 November 2021 – Transforming growth factor beta (TGF‐β) plays a key role in tumor progression, notably as a potent inducer of epithelial–mesenchymal transition (EMT). However, all of the molecular effectors driving TGFβ‐induced EMT are not fully characterized.

High‐Resolution Exposomics and Metabolomics Reveals Specific Associations in Cholestatic Liver Diseases

Douglas I. Walker, Brian D. Juran, Angela C. Cheung, Erik M. Schlicht, Yongliang Liang, Megan Niedzwiecki, Nicholas F. LaRusso, Gregory J. Gores, Dean P. Jones, Gary W. Miller, Konstantinos N. Lazaridis – 25 November 2021 – Progress in development of prognostic and therapeutic options for the rare cholestatic liver diseases, primary sclerosing cholangitis (PSC) and primary biliary cholangitis (PBC), is hampered by limited knowledge of their pathogeneses.

Organ‐Specific Comorbidities Are Associated With Distinct Complications After Liver Transplantation for Biliary Atresia

Sarah A. Taylor, Veena Venkat, Ronen Arnon, Vani V. Gopalareddy, Philip Rosenthal, Sarah G. Anderson, Ravinder Anand, James F. Daniel, Society of Pediatric Liver Transplantation – 24 November 2021 – Although transplant outcomes for biliary atresia (BA) have improved, there are few data to predict the risk of specific posttransplant complications. We therefore defined the impact of comorbidities in BA on posttransplant outcomes.

Subscribe to