Severe Alcohol‐Associated Hepatitis Is Associated With Worse Survival in Critically Ill Patients With Acute on Chronic Liver Failure

Kavish R. Patidar, Jennifer L. Peng, Harleen Kaur, Astin Worden, Carla D. Kettler, Francis Pike, Caitriona A. Buckley, Eric S. Orman, Archita P Desai, Lauren D. Nephew, Chandrashekhar A. Kubal, Samer Gawrieh, Naga Chalasani, Marwan S. Ghabril – 2 December 2021 – Differences in mortality between critically ill patients with severe alcohol‐associated hepatitis (sAH) and acute‐on‐chronic liver failure (ACLF) and non‐sAH ACLF (i.e., ACLF not precipitated by sAH) are unknown. Such differences are important, as they may inform on prognosis and optimal timing of liver transplantation (LT).

Secondary Prophylaxis of Gastric Variceal Bleeding: A Systematic Review and Network Meta‐Analysis

Karim T. Osman, Tarek Nayfeh, Ahmed M. Abdelfattah, Khaled Alabdallah, Bashar Hasan, Mohammed Firwana, Homam Alabaji, Lina Elkhabiry, Jehan Mousa, Larry J. Prokop, M. Hassan Murad, Fredric Gordon – 2 December 2021 – There is no clear consensus regarding the optimal approach for secondary prophylaxis of gastric variceal bleeding (GVB) in patients with cirrhosis. We conducted a systematic review and network meta‐analysis (NMA) to compare the efficacy of available treatments.

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Andrew I. Aronsohn, Debika Bhattacharya, Timothy R. Morgan, David L. Wyles, Raymond T. Chung, Daniel P. McQuillen, AASLD‐IDSA HCV Guidance – 2 December 2021

Sphingosine‐1‐phosphate promotes tumor development and liver fibrosis in mouse model of congestive hepatopathy

Hironari Kawai, Yosuke Osawa, Michitaka Matsuda, Tomoyuki Tsunoda, Keisuke Yanagida, Daisuke Hishikawa, Miku Okawara, Yuzuru Sakamoto, Tomonari Shimagaki, Yuriko Tsutsui, Yuichi Yoshida, Shiori Yoshikawa, Kana Hashi, Hiroyoshi Doi, Taizo Mori, Taiji Yamazoe, Sachiyo Yoshio, Masaya Sugiyama, Daisuke Okuzaki, Haruki Komatsu, Ayano Inui, Miwa Tamura‐Nakano, Chinatsu Oyama, Hideo Shindou, Hironori Kusano, Masayoshi Kage, Toru Ikegami, Katsuhiko Yanaga, Tatsuya Kanto – 1 December 2021

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