Alcohol-associated liver disease (ALD) represents a spectrum of liver injury resulting from alcohol use, ranging from hepatic steatosis to more advanced forms including alcoholic hepatitis (AH), alcohol-associated cirrhosis (AC), and acute AH presenting as acute-on-chronic liver failure.
Tingting Yan, Yuhong Luo, Nana Yan, Keisuke Hamada, Nan Zhao, Yangliu Xia, Ping Wang, Changdong Zhao, Dan Qi, Shoumei Yang, Lulu Sun, Jie Cai, Qiong Wang, Changtao Jiang, Oksana Gavrilova, Kristopher W. Krausz, Daxesh P. Patel, Xiaoting Yu, Xuan Wu, Haiping Hao, Weiwei Liu, Aijuan Qu, Frank J. Gonzalez – 22 April 2022
Histological assessment of the liver, and thus, liver biopsy, is a cornerstone in the evaluation and management of patients with liver disease and has long been considered to be an integral component of the clinician’s diagnostic armamentarium.
The advent of safe, well-tolerated, and highly efficacious (>95% cure rate) direct-acting antiviral (DAA) therapy for hepatitis C virus (HCV) infection has ushered in an era in which elimination of hepatitis C is conceivable.
Hepatic decompensation, defined by ascites, hepatic encephalopathy, and portal hypertensive gastrointestinal bleeding, is an important landmark in the natural history of cirrhosis.
The diagnosis of acute liver failure (ALF) hinges on identifying that the patient has an acute insult and is encephalopathic.
21 April 2022
21 April 2022
Won Sriwijitalai, Viroj Wiwanitkit – 21 April 2022