Explore innovative management strategies for pediatric patients with autoimmune liver diseases at this exciting symposium. Faculty will review the pathophysiology, diagnosis, management, and risk stratification of pediatric AIH and PSC. Talks will focus on diagnosis, primary and secondary lines of therapy, complex cases, pediatric-specific predictive models, and post-transplant disease recurrence. Preliminary results of recent clinical trials will be objectively presented.

Blood coagulation in drug-induced liver injury (DILI) is an emerging hot topic in basic and clinical research, and clinical practice. Physicians and basic scientists will review recent discoveries in molecular and cellular mechanisms of DILI blood coagulation, optimal clinical management of patients with acute and chronic liver diseases, and experimental animal models on Von Willebrand factor and platelets in DILI.

Don’t overlook any of the research presented at The Liver Meeting® 2021 that directly impacts patients. This year's debrief will briefly review of all the abstracts presented at the meeting that significantly impacted the role of the patient in one condensed session.

This presentation will discuss emerging concepts in our understanding of the pathogenesis of alcohol related hepatotoxicity and how it could inform therapeutic approaches.

There is a growing awareness that behavioral health interventions can improve outcomes for patients with chronic liver disease (CLD). This seminar examines the role of behavioral health in CLD care, existing disparities in behavioral health care access, and proposed plans to integrate these interventions and overcome care gaps to improve the health and well-being of CLD patients.

Justification for use of non-histopathological approaches for monitoring chronic necro-inflammatory liver diseases is based on comparison to traditional pathology.  Recent advances in cross-platform analyses enable a unique integrated approach to study liver-based immune responses while (1) retaining a micron-level spatial context resolution scale; (2) incorporating multiplex labeling, digital imaging and analysis; (3) mRNA expression and mutational profiling;  and (4) serology.

Value-based arrangements are a rising trend in healthcare. Providers in all professional settings are learning to adapt and thrive in this new landscape. This program will educate and empower hepatologists to contribute to successful, value-based care arrangements, including talks on the role that clinical trials and palliative care can play in value preservation at all stages of liver disease.

It is absolutely essential to foster health disparities research to reduce disparities, and improve outcomes among ethnic and racial groups with a higher burden of liver disease, and expand the pool of under-represented minorities (URM) within hepatology. The Diversity Workshop’s goals are to educate practitioners, provide tools to develop diverse clinical and research programs, and promote cultural competency within hepatology.

How can gut-liver axis disruption trigger progression of chronic liver disease? Gain deeper insights on the gut-liver axis, an essential reciprocal interaction between the gut, microbiota and the liver. Presentations cover how bile acids regulate the composition of microbiota and intestinal barrier function, and how gut products regulate bile acid synthesis, and glucose and lipid metabolism in the liver.

The healthcare burden of alcohol-associated liver disease (ALD) is rising, especially in younger adults and women, with worrying ethnic and racial disparities in ALD burden. Epidemic metabolic risk factors and obesity seem to drive higher prevalence of both ALD and NAFLD. This symposium will address ALD in special at-risk populations and how hepatologists can effectively diagnose and manage these patients.