Role of Novel Kidney Biomarkers in Patients With Cirrhosis and After Liver Transplantation

Sumeet K. Asrani, Nagasri Shankar, Briget Graca, Mitra K. Nadim, Andres Cardenas – 28 October 2021 – Acute kidney injury (AKI) and chronic kidney disease (CKD) are important drivers of morbidity and mortality in patients with cirrhosis before and after liver transplantation (LT). In this review, we examine the role of novel kidney biomarkers for early recognition of kidney injury. Studies are limited by lack of reference standards, heterogeneous definitions of outcomes and biomarker cutoffs, and inconsistent diagnostic performance.

Validation of Dynamic Aspartate‐to–Alanine Aminotransferase Ratio for Predicting Liver Disease Mortality

In‐Ae Song, Eun Sun Jang, Tak Kyu Oh – 28 October 2021 – The dynamic aspartate‐to–alanine aminotransferase ratio (dAAR) was developed recently to predict the risk of incident chronic liver disease among the Nordic adult population; however, the dAAR has not been externally validated in other ethnic cohorts. Therefore, we aimed to examine the predictive ability of dAAR for liver disease mortality in the South Korean adult population.

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