Luis Montano, Fernando Aranguibel, Margarita Boffill, Alison H. Goodall, George Janossy, Howard C. Thomas – 1 January 1983 – The composition of the mononuclear cell infiltrate in the liver was studied in patients with autoimmune and hepatitis B virus (HBV)‐induced liver disease. The ratio of inducer to cytotoxic/ suppressor cells was greater in patients with lupoid chronic active liver disease, primary biliary cirrhosis, and HBeAb positive HBV‐induced chronic active liver disease than in patients with HBeAg positive HBV‐induced chronic hepatitis.

Charles S Davidson, Milton M. Weiser – 1 January 1983

Robert S. Mccuskey, Franz J. Vonnahme, Martin Grun – 1 January 1983 – The livers of rats subjected to end‐to‐side portacaval anastomoses were studied 3 to 5 months postoperatively by in vivo and electron microscopy. Compared with sham‐operated controls, the livers of portacaval anastomoses animals contained dilated, tortuous networks of sinusoids. The velocity of blood flow in these vessels tended to be slower and more variable than controls, but always progressed toward the hepatic venules.

Ellen I. Kahn, Fredric Daum, James Markowitz, Harvey W. Aiges, Keith M. Schneider, Henry B. So, Peter Altman, Roma S. Chandra, Mervin Silverberg – 1 January 1983 – Five children were noted to have arteriohepatic dysplasia (Alagille's syndrome) between 3 and 7 months of age. Prior to diagnosis, four underwent Kasai procedures after intraoperative cholangio‐grams failed to demonstrate patency of the extrahepatic bile ducts. In three patients, a focal proximal hypoplasia of the common hepatic duct was demonstrated with fibrosis and increased vascularity.

Carmen Viola, Lydia Vineta, Jaime Bosch, Juan Rodés – 1 January 1983 – Two patients who presented with an exudative ascites in the course of typical acute type B hepatitis are reported. In one of them, ascites was associated with an exudative pleural effusion. In both patients, the clinical course of the hepatitis was uneventful, and ascites and pleural effusion disappeared spontaneously. Portal hypertension and common causes of exudative ascites were excluded.

Chia‐Ming Chu, Yun‐Fan Liaw, I‐Shyan Sheen, Deng‐Yn Lin, Miau‐Ju Huang – 1 January 1983 – Hepatitis B e antigen (HBeAg) and antibody (anti‐HBe) were studied by radioimmunoassay in consecutive series of 145 asymptomatic hepatitis B surface antigen (HBsAg) carriers, 389 patients with HBsAg‐positive chronic liver disease and 194 patients with HBsAg‐positive hepatocellular carcinoma, and compared between male and female subjects. The male to female ratio increased from 1.2 in asymptomatic carriers to 6.3 in chronic liver disease and 9.8 in hepatocellular carcinoma.

Lis Fauerholdt, Poul Schlichting, Erik Christensen, Hemming Poulsen, Niels Tygstrup, Erik Juhl, The Copenhagen Study Group FOR Liver Diseases – 1 January 1983 – The conversion from micro‐ to macronodular cirrhosis is claimed to be a general phenomenon. In this study, the conversion was quantitated by means of liver needle follow‐up biopsies and autopsy in 156 patients followed in a controlled clinical trial of prednisone treatment in cirrhosis.

1 January 1983

Robert A. F. M. Chamuleau, Robert J. Popken, Ellen C. Beyerbacht, Henk W. M. De Koning – 1 January 1983 – Acute hepatic failure was induced in rats by galactosamine injection intraperitoneally (1 gm per kg). Twenty‐four hours later rats were treated by hemoperfusion (HP) over encapsulated sorbents: cellulose acetate‐coated charcoal, polyelectrolyte‐coated XAD4, a combination of both, or cross circulation with a healthy donor. Compared with control treatment (prevention of hypoglycemia by glucose infusion), the survival rate was not improved by HP or cross circulation: controls 19% vs.

1 January 1983