Application of Artificial Intelligence for the Diagnosis and Treatment of Liver Diseases

Joseph C. Ahn, Alistair Connell, Douglas A. Simonetto, Cian Hughes, Vijay H. Shah – 23 October 2020 – Modern medical care produces large volumes of multimodal patient data, which many clinicians struggle to process and synthesize into actionable knowledge. In recent years, artificial intelligence (AI) has emerged as an effective tool in this regard. The field of hepatology is no exception, with a growing number of studies published that apply AI techniques to the diagnosis and treatment of liver diseases.

Triple‐Phase Computed Tomography May Replace Dual‐Energy X‐ray Absorptiometry Scan for Evaluation of Osteoporosis in Liver Transplant Candidates

Manhal Izzy, Benyam D. Addissie, Juan Pablo Arab, Moira B. Hilscher, Amanda Cartee, David C. Lee, Yong Lee, Joel G. Fletcher, Tony M. Keaveny, William Sanchez – 23 October 2020 – Assessment of bone density is an important part of liver transplantation (LT) evaluation for early identification and treatment of osteoporosis. Dual‐energy X‐ray absorptiometry (DXA) is currently the standard clinical test for osteoporosis; however, it may contribute to the appointment burden on LT candidates during the cumbersome evaluation process, and there are limitations affecting its accuracy.

Coagulopathy in Malnourished Mice Is Sexually Dimorphic and Regulated by Nutrient‐Sensing Nuclear Receptors

Geoffrey A. Preidis, Krishnakant G. Soni, Ji Ho Suh, Tripti Halder, Kang Ho Kim, Jong Min Choi, Feng Li, Sridevi Devaraj, Margaret E. Conner, Cristian Coarfa, Sung Yun Jung, David D. Moore – 22 October 2020 – Liver dysfunction, including coagulopathy, is a prominent feature of protein‐energy malnutrition. To identify mechanisms underlying malnutrition‐associated coagulopathy, we administered a low‐protein low‐fat diet to lactating dams and examined hepatic transcription and plasma coagulation parameters in young adult weanlings.

Consequences of Perioperative Serotonin Reuptake Inhibitor Treatment During Hepatic Surgery

Patrick Starlinger, David Pereyra, Hubert Hackl, Gregor Ortmayr, Eva Braunwarth, Jonas Santol, Sina Najarnia, Michael R. Driedger, Lindsey Gregory, Roberto Alva‐Ruiz, Amy Glasgow, Alice Assinger, David M. Nagorney, Elizabeth B. Habermann, Stefan Staetttner, Sean P. Cleary, Rory L. Smoot, Thomas Gruenberger – 20 October 2020

Liver Metastases of Intrahepatic Cholangiocarcinoma: Implications for an Updated Staging System

Angela Lamarca, Alvaro Santos‐Laso, Kirsten Utpatel, Adelaida La Casta, Simone Stock, Alejandro Forner, Jorge Adeva, Trine Folseraas, Luca Fabris, Rocio I.R. Macias, Marcin Krawczyk, Marek Krawczyk, Vincenzo Cardinale, Chiara Braconi, Domenico Alvaro, Matthias Evert, Jesus M. Banales, Juan W. Valle, for the Group: on behalf of the European Network for the Study of Cholangiocarcinoma (ENS‐CCA) – 18 October 2020

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