Cancer‐Associated Fibroblast‐Mediated Cellular Crosstalk Supports Hepatocellular Carcinoma Progression

Mengjia Song, Junyi He, Qiu‐Zhong Pan, Jieying Yang, Jingjing Zhao, Yao‐Jun Zhang, Yue Huang, Yan Tang, Qijing Wang, Jia He, Jiamei Gu, Yongqiang Li, Shiping Chen, Jianxiong Zeng, Zi‐Qi Zhou, Chaopin Yang, Yulong Han, Hao Chen, Tong Xiang, De‐Sheng Weng, Jian‐Chuan Xia – 7 March 2021

A Dynamic Aspartate‐to‐Alanine Aminotransferase Ratio Provides Valid Predictions of Incident Severe Liver Disease

Fredrik Åberg, Christopher J. Danford, Maja Thiele, Mats Talbäck, Ditlev Nytoft Rasmussen, Z. Gordon Jiang, Niklas Hammar, Patrik Nasr, Mattias Ekstedt, Anna But, Pauli Puukka, Aleksander Krag, Jouko Sundvall, Iris Erlund, Veikko Salomaa, Per Stål, Stergios Kechagias, Rolf Hultcrantz, Michelle Lai, Nezam Afdhal, Antti Jula, Satu Männistö, Annamari Lundqvist, Markus Perola, Martti Färkkilä, Hannes Hagström – 7 March 2021 – The aspartate‐to‐alanine aminotransferase ratio (AAR) is associated with liver fibrosis, but its predictive performance is suboptimal.

Metabolomic Analysis Uncovers Energy Supply Disturbance as an Underlying Mechanism of the Development of Alcohol‐Associated Liver Cirrhosis

Ying Huang, Ming Niu, Jing Jing, Zi‐teng Zhang, Xu Zhao, Shuai‐shuai Chen, Shan‐shan Li, Zhuo Shi, Ang Huang, Zheng‐Sheng Zou, Yue‐cheng Yu, Xiao‐he Xiao, Suthat Liangpunsakul, Jia‐bo Wang – 7 March 2021 – Alcohol‐associated liver disease (ALD) is caused by alcohol metabolism’s effects on the liver. The underlying mechanisms from a metabolic view in the development of alcohol‐associated liver cirrhosis (ALC) are still elusive.

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