The Predictive Role of Model for End‐Stage Liver Disease–Lactate and Lactate Clearance for In‐Hospital Mortality Among a National Cirrhosis Cohort

Nadim Mahmud, Sumeet K. Asrani, David E. Kaplan, Gerald O. Ogola, Tamar H. Taddei, Patrick S. Kamath, Marina Serper – 6 October 2020 – The burden of cirrhosis hospitalizations is increasing. The admission Model for End‐Stage Liver Disease–lactate (MELD‐lactate) was recently demonstrated to be a superior predictor of in‐hospital mortality compared with MELD in limited cohorts. We identified specific classes of hospitalizations where MELD‐lactate may be especially useful and evaluated the predictive role of lactate clearance.

A Model Based on Noninvasive Markers Predicts Very Low Hepatocellular Carcinoma Risk After Viral Response in Hepatitis C Virus–Advanced Fibrosis

Sonia Alonso López, María Luisa Manzano, Francisco Gea, María Luisa Gutiérrez, Adriana Maria Ahumada, María José Devesa, Antonio Olveira, Benjamin Arturo Polo, Laura Márquez, Inmaculada Fernández, Juan Carlos Ruiz Cobo, Laura Rayón, Daniel Riado, Sonia Izquierdo, Clara Usón, Yolanda Real, Diego Rincón, Conrado M. Fernández‐Rodríguez, Rafael Bañares – 6 October 2020

Long‐Term Safety and Efficacy of Pure Laparoscopic Donor Hepatectomy in Pediatric Living Donor Liver Transplantation

Wan‐Joon Kim, Ki‐Hun Kim, Hwui‐Dong Cho, Jung‐Man Namgoong, Shin Hwang, Jeong‐Ik Park, Sung‐Gyu Lee – 5 October 2020 – Laparoscopic living donor hepatectomy for transplantation has been well established over the past decade. This study aimed to assess its safety and feasibility in pediatric living donor liver transplantation (LDLT) by comparing the surgical and long‐term survival outcomes on both the donor and recipient sides between open and laparoscopic groups.

Epigenome‐Wide Analysis of Methylation Changes in the Sequence of Gallstone Disease, Dysplasia, and Gallbladder Cancer

Johannes Brägelmann, Carol Barahona Ponce, Katherine Marcelain, Stephanie Roessler, Benjamin Goeppert, Ivan Gallegos, Alicia Colombo, Verónica Sanhueza, Erik Morales, María Teresa Rivera, Gonzalo Toro, Alejandro Ortega, Bettina Müller, Fernando Gabler, Dominique Scherer, Melanie Waldenberger, Eva Reischl, Felix Boekstegers, Valentina Garate‐Calderon, Sinan U. Umu, Trine B. Rounge, Odilia Popanda, Justo Lorenzo Bermejo – 5 October 2020

Modeling Outcomes in Children With Biliary Atresia With Native Liver After 2 Years of Age

Veena Venkat, Vicky L. Ng, John C. Magee, Wen Ye, Kieran Hawthorne, Sanjiv Harpavat, Jean P. Molleston, Karen F. Murray, Kasper S. Wang, Nisreen Soufi, Lee M. Bass, Estella M. Alonso, Jorge A. Bezerra, M. Kyle Jensen, Binita M. Kamath, Kathleen M. Loomes, Cara L. Mack, Philip Rosenthal, Benjamin L. Shneider, Robert H. Squires, Ronald J. Sokol, Saul J. Karpen, for the Childhood Liver Disease Research Network – 3 October 2020 – Approximately 50% of infants with biliary atresia (BA) undergoing Kasai portoenterostomy show survival with native liver (SNL) at age 2 years.

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