DNA Methylation of Cannabinoid Receptor Interacting Protein 1 Promotes Pathogenesis of Intrahepatic Cholangiocarcinoma Through Suppressing Parkin‐Dependent Pyruvate Kinase M2 Ubiquitination

Diyu Chen, Hao Wu, Xiaode Feng, Yunhao Chen, Zhen Lv, Vishnu Goutham Kota, Junru Chen, Wenxuan Wu, Yuejie Lu, Hua Liu, Yanpeng Zhang, Shusen Zheng, Jian Wu – 21 September 2020

Consequences of Extended Spectrum Beta‐Lactamase–Producing Enterobacteriaceae and Methicillin‐Resistant Staphylococcus aureus Carriage in Awaiting Liver Transplant Patients

Bianca Magro, Alessandra Mazzola, Mona Munteanu, Claire Goumard, Valerie Martinez, Denis Bernard, Olivier Scatton, Salvatore Battaglia, Ciro Celsa, Calogero Cammà, Filomena Conti – 21 September 2020 – Infections in patients with cirrhosis are associated with liver‐related complications (LRCs), especially in patients awaiting liver transplantation (LT). The aim of this study was to evaluate the impact of methicillin‐resistant Staphylococcus aureus (MRSA) and extended spectrum beta‐lactamase colonization on infections and LRCs for patients on the wait list and on infections after LT.

LiverLearning®: 2020 Webinar: Current and Future Disease Burden of HBV: Global and Regional Perspectives

In this on-demand webinar, representative speakers from Africa including North and Sub-Saharan Africa (Mark W. Sonderup, South Africa), East Asia (Jidong Jia, China), West and South Asia (Shiv K. Sarin, India), Europe including Western and Eastern Europe (George V. Papatheodoridis, Greece), North America (Carla Coffin, Canada) and South/Central America (Adrian Gadano) will each talk on HBV disease burden and primary challenges in their respective regions. They will present the current status and predictions for the next decade.

Oral Vancomycin, Ursodeoxycholic Acid, or No Therapy for Pediatric Primary Sclerosing Cholangitis: A Matched Analysis

Mark R. Deneau, Cara Mack, Douglas Mogul, Emily R. Perito, Pamela L. Valentino, Achiya Z. Amir, Matthew DiGuglielmo, Laura G. Draijer, Wael El‐Matary, Katryn N. Furuya, Nitika Gupta, Jessica T. Hochberg, Simon Horslen, M. Kyle Jensen, Maureen M. Jonas, Nanda Kerkar, Bart G.P. Koot, Trevor J. Laborda, Christine K. Lee, Kathleen M. Loomes, Mercedes Martinez, Alexander Miethke, Tamir Miloh, Saeed Mohammad, Nadia Ovchinsky, Girish Rao, Amanda Ricciuto, Pushpa Sathya, Kathleen B. Schwarz, Uzma Shah, Ruchi Singh, Bernadette Vitola, Andréanne Zizzo, Stephen L. Guthery – 18 September 2020

Patient Frailty Is Independently Associated With the Risk of Hospitalization for Acute‐on‐Chronic Liver Failure

Shivani Shah, David S. Goldberg, David E. Kaplan, Vinay Sundaram, Tamar H. Taddei, Nadim Mahmud – 18 September 2020 – There is significant interest in identifying risk factors associated with acute‐on‐chronic liver failure (ACLF). In transplant candidates, frailty predicts wait‐list mortality and posttransplant outcomes. However, the impact of frailty on ACLF development and mortality is unknown. This was a retrospective study of US veterans with cirrhosis identified between 2008 and 2016. First hospitalizations were characterized as ACLF or non‐ACLF admissions.

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