Patient Frailty Is Independently Associated With the Risk of Hospitalization for Acute‐on‐Chronic Liver Failure
Shivani Shah, David S. Goldberg, David E. Kaplan, Vinay Sundaram, Tamar H. Taddei, Nadim Mahmud – 18 September 2020 – There is significant interest in identifying risk factors associated with acute‐on‐chronic liver failure (ACLF). In transplant candidates, frailty predicts wait‐list mortality and posttransplant outcomes. However, the impact of frailty on ACLF development and mortality is unknown. This was a retrospective study of US veterans with cirrhosis identified between 2008 and 2016. First hospitalizations were characterized as ACLF or non‐ACLF admissions.