Issue Information
3 February 2020
Inadequate Physical Activity and Sedentary Behavior Are Independent Predictors of Nonalcoholic Fatty Liver Disease
Donghee Kim, Luis Miguel Vazquez‐Montesino, Andrew A. Li, George Cholankeril, Aijaz Ahmed – 3 February 2020
Noninvasive Testing Using Magnetic Resonance Imaging Techniques as Outcomes in Nonalcoholic Steatohepatitis Clinical Trials: How Full Is the Glass?
Nabil Noureddin, Jörn M. Schattenberg, Naim Alkhouri, Mazen Noureddin – 3 February 2020
Kidney Graft Outcomes in High Immunological Risk Simultaneous Liver‐Kidney Transplants
Gastón J. Piñeiro, Jordi Rovira, Enrique Montagud‐Marrahí, Jose V. Torregrosa, José Ríos, David Cucchiari, Jessica Ugalde‐Altamirano, Pedro Ventura‐Aguiar, Rosana Gelpi, Eduard Palou, Jordi Colmenero, Miquel Navasa, Fritz Diekmann, Nuria Esforzado – 3 February 2020 – Recipients of simultaneous liver‐kidney transplantations (SLKTs) have a lower risk of rejection compared with recipients of kidney transplants alone. However, there is disagreement about the impact of pretransplant anti–human leukocyte antigen sensitization on patient and kidney graft survival in the long term.
Recurrent Isolated Hyperbilirubinemia From Drug‐Induced Impaired Hepatic Bilirubin Uptake
Alick Feng, Maen Masadeh, Arvind R. Murali – 31 January 2020
Recurrent Isolated Hyperbilirubinemia From Drug‐Induced Impaired Hepatic Bilirubin Uptake
Alick Feng, Maen Masadeh, Arvind R. Murali – 31 January 2020
Taming the Savage Breast From Within: Transcription Factor 21, a Regulator of Stellate Cell Deactivation
Shuang Wang, Scott L. Friedman – 31 January 2020
New Insights Into Intestinal Failure–Associated Liver Disease in Children
Racha T. Khalaf, Ronald J. Sokol – 31 January 2020 – Development of intestinal failure–associated liver disease (IFALD) is a common complication of long‐term parenteral nutrition (PN) in children and adults. The molecular and cellular mechanisms and the phases of IFALD are now being delineated. Components of PN lipid emulsions, including plant sterols, interact with hepatic innate immune activation promoted by products of gut bacterial overgrowth/dysbiosis and altered intestinal barrier function (gut‐liver axis) and by episodes of sepsis to cause cholestasis and IFALD.
New Insights Into Intestinal Failure–Associated Liver Disease in Children
Racha T. Khalaf, Ronald J. Sokol – 31 January 2020 – Development of intestinal failure–associated liver disease (IFALD) is a common complication of long‐term parenteral nutrition (PN) in children and adults. The molecular and cellular mechanisms and the phases of IFALD are now being delineated. Components of PN lipid emulsions, including plant sterols, interact with hepatic innate immune activation promoted by products of gut bacterial overgrowth/dysbiosis and altered intestinal barrier function (gut‐liver axis) and by episodes of sepsis to cause cholestasis and IFALD.
A Single‐Cell Perspective of the Mammalian Liver in Health and Disease
Xuelian Xiong, Henry Kuang, Tongyu Liu, Jiandie D. Lin – 30 January 2020