The Impact of COVID‐19 on Organ Donation, Procurement, and Liver Transplantation in the United States

Jonathan Merola, Michael L. Schilsky, David C. Mulligan – 29 September 2020 – The coronavirus disease 2019 pandemic has had an impact on all facets of our health care system, including life‐saving procedures like organ transplantation. Concerns for potential exposure to the causative severe acute respiratory syndrome coronavirus type 2 have profoundly altered the process of organ donation and recovery that is vital to the execution of organ transplantation.

The Impact of COVID‐19 on Organ Donation, Procurement, and Liver Transplantation in the United States

Jonathan Merola, Michael L. Schilsky, David C. Mulligan – 29 September 2020 – The coronavirus disease 2019 pandemic has had an impact on all facets of our health care system, including life‐saving procedures like organ transplantation. Concerns for potential exposure to the causative severe acute respiratory syndrome coronavirus type 2 have profoundly altered the process of organ donation and recovery that is vital to the execution of organ transplantation.

Osteopontin Takes Center Stage in Chronic Liver Disease

Zhuolun Song, Wei Chen, Dipti Athavale, Xiaodong Ge, Romain Desert, Sukanta Das, Hui Han, Natalia Nieto – 28 September 2020 – Osteopontin (OPN) was first identified in 1986. The prefix osteo‐ means bone; however, OPN is expressed in other tissues, including liver. The suffix ‐pontin means bridge and denotes the role of OPN as a link protein within the extracellular matrix. While OPN has well‐established physiological roles, multiple “omics” analyses suggest that it is also involved in chronic liver disease.

Hepatology Highlights

Alyson Kaplan, Russell Rosenblatt, Adam Buckholz, Sonal Kumar, Gopanandan Parthasarathy, Robert E. Schwartz, Petra Hirsova, Robert E. Schwartz, Joseph F. Pisa, Robert S. Brown, Nidhi Jalan‐Sakrikar, Robert E. Schwartz, Arun B. Jesudian, Nicholas W. Russo, Chaitanya Allamneni, Ravi S. Vora, Enis Kostallari, Robert E. Schwartz – 28 September 2020

Hepatology Highlights

Alyson Kaplan, Russell Rosenblatt, Adam Buckholz, Sonal Kumar, Gopanandan Parthasarathy, Robert E. Schwartz, Petra Hirsova, Robert E. Schwartz, Joseph F. Pisa, Robert S. Brown, Nidhi Jalan‐Sakrikar, Robert E. Schwartz, Arun B. Jesudian, Nicholas W. Russo, Chaitanya Allamneni, Ravi S. Vora, Enis Kostallari, Robert E. Schwartz – 28 September 2020

Reducing the Global Burden of Alcohol‐Associated Liver Disease: A Blueprint for Action

Sumeet K. Asrani, Jessica Mellinger, Juan P. Arab, Vijay H. Shah – 28 September 2020 – Alcohol‐associated liver disease (ALD) is a major driver of global liver related morbidity and mortality. There are 2.4 billion drinkers (950 million heavy drinkers) and the lifetime prevalence of any alcohol use disorder (AUD) is 5.1%‐8.6%. In 2017, global prevalence of alcohol‐associated compensated and decompensated cirrhosis was 23.6 million and 2.5 million, respectively.

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