New Drugs for NASH and HIV Infection: Great Expectations for a Great Need

Giovanni Guaraldi, James B. Maurice, Catia Marzolini, Kenneth Monteith, Jovana Milic, Emmanuel Tsochatzis, Sanjay Bhagani, Caryn G. Morse, Jennifer C. Price, Patrick Ingiliz, Maud Lemoine, Giada Sebastiani, the SHIVER Network – 13 February 2020 – In recent years, there has been an increasing number of clinical trials for the treatment of nonalcoholic steatohepatitis (NASH). People living with human immunodeficiency virus (PLWH) are commonly excluded from these studies, usually due to concerns over drug–drug interactions associated with antiretroviral therapy.

Biomarkers for Hepatobiliary Cancers

Jean‐Charles Nault, Augusto Villanueva – 11 February 2020 – The clinical management of primary liver cancers such as hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCA) has significantly changed in the last 3 years. The introduction of systemic therapies, including immune‐based therapies and biomarker‐driven therapies, has significantly improved survival, particularly in patients at advanced stages of disease. Survival is still poor, and projections from the World Health Organization underscore the need to improve outcomes in these patients.

Hepatology Highlights

Alyson Kaplan, Russell Rosenblatt, Nicholas W. Russo, Robert S. Brown, Joseph F. Pisa, Petra Hirsova, Robert E. Schwartz, Enis Kostallari, Nidhi Jalan‐Sakrikar, Rajab Idriss, Hirsh Trivedi, Daryl T.Y. Lau, Amaia Navarro‐Corcuera – 10 February 2020

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