James Neuberger – 26 March 2019

Bianca E. Russell, Kaitlin G. Whaley, Kevin E. Bove, Anatalia Labilloy, Rachel C. Lombardo, Robert J. Hopkin, Nancy D. Leslie, Carlos Prada, Zahra Assouline, Giulia Barcia, Juliette Bouchereau, Maryline Chomton, Dominique Debray, Imen Dorboz, Philippe Durand, Pauline Gaignard, Dalila Habes, Claude Jardel, François Labarthe, Jonathan Lévy, Anne Lombès, Claire Mehler‐Jacob, Judith Melki, Laura Menvielle, Arnold Munnich, Charlotte Mussini, Samia Pichard, Marlène Rio, Agnès Rötig, Samira Sissaoui, Abdelhamid Slama, Alexander G Miethke, Manuel Schiff – 26 March 2019

Giovanni Targher, Alessandro Mantovani, Anna Alisi, Antonella Mosca, Nadia Panera, Christopher D. Byrne, Valerio Nobili – 26 March 2019 – Emerging evidence suggests that patatin‐like phospholipase domain–containing protein‐3 (PNPLA3) rs738409 genotype (the major genetic variant associated with susceptibility to nonalcoholic fatty liver disease [NAFLD]) is associated with decreased kidney function in adults. Currently, it is uncertain whether this association also occurs in children/adolescents and whether any association is independent of liver disease severity.

Bianca E. Russell, Kaitlin G. Whaley, Kevin E. Bove, Anatalia Labilloy, Rachel C. Lombardo, Robert J. Hopkin, Nancy D. Leslie, Carlos Prada, Zahra Assouline, Giulia Barcia, Juliette Bouchereau, Maryline Chomton, Dominique Debray, Imen Dorboz, Philippe Durand, Pauline Gaignard, Dalila Habes, Claude Jardel, François Labarthe, Jonathan Lévy, Anne Lombès, Claire Mehler‐Jacob, Judith Melki, Laura Menvielle, Arnold Munnich, Charlotte Mussini, Samia Pichard, Marlène Rio, Agnès Rötig, Samira Sissaoui, Abdelhamid Slama, Alexander G Miethke, Manuel Schiff – 26 March 2019

Vinay Sundaram, Parth Shah, Robert J. Wong, Constantine J. Karvellas, Brett E. Fortune, Nadim Mahmud, Alexander Kuo, Rajiv Jalan – 25 March 2019 – Patients listed for liver transplantation (LT) as status 1a currently receive the highest priority on the waiting list. The presence of acute on chronic liver failure (ACLF) with three or more organs failing (ACLF‐3) portends low survival without transplantation, which may not be reflected by the Model for End‐Stage Liver Disease‐Sodium (MELD‐Na) score.

Jie Yang, Eric Trépo, Pierre Nahon, Qian Cao, Christophe Moreno, Eric Letouzé, Sandrine Imbeaud, Quentin Bayard, Thierry Gustot, Jacques Deviere, Paulette Bioulac‐Sage, Julien Calderaro, Nathalie Ganne‐Carrié, Alexis Laurent, Jean Frédéric Blanc, Erwan Guyot, Angela Sutton, Marianne Ziol, Jessica Zucman‐Rossi, Jean‐Charles Nault – 25 March 2019 – Recently, a loss of function variant (rs72613567) in 17‐beta‐hydroxysteroid dehydrogenase 13 (HSD17B13) has been identified as protective of nonalcoholic (NAFLD) and alcoholic liver disease (ALD).

Florence Wong, K. Rajender Reddy, Jacqueline G. O’Leary, Puneeta Tandon, Scott W. Biggins, Guadalupe Garcia‐Tsao, Benedict J. Maliakkal, Jennifer C. Lai, Michael B. Fallon, Hugo E. Vargas, Ram Subramanian, Paul J. Thuluvath, Patrick S. Kamath, Leroy Thacker, Jasmohan S. Bajaj – 25 March 2019 – We hypothesize that the prevalence of chronic kidney disease (CKD) among patients with cirrhosis has increased due to the increased prevalence of CKD‐associated comorbidities, such as diabetes.

Alexander Y. Pan, Lauren D. Feld, Jeanne M. Farnan, Steven K. Herrine, Adam E. Mikolajczyk – 25 March 2019

Cindy Piao, Norah A. Terrault, Souvik Sarkar – 25 March 2019 – Healthcare delivery has been dramatically changing in recent times with advances in technology. One area of expansion has been the use of telemedicine due to progression in communication technologies. Telemedicine offers the opportunity to overcome barriers of access, improve patient satisfaction, improve healthcare outcomes and streamline communication between patients and providers.

Yanyong Xu, Yingdong Zhu, Kavita Jadhav, Yuanyuan Li, Huihui Sun, Liya Yin, Takhar Kasumov, Xiaoli Chen, Yanqiao Zhang – 25 March 2019 – Hepatocytes are the major source of hepatic lipocalin‐2 (LCN2), which is up‐regulated in response to inflammation, injury, or metabolic stress. So far, the role of hepatocyte‐derived LCN2 in the development of nonalcoholic fatty liver disease (NAFLD) remains unknown.