Hydrogen Flush After Cold Storage as a New End‐Ischemic Ex Vivo Treatment for Liver Grafts Against Ischemia/Reperfusion Injury

Ichiro Tamaki, Koichiro Hata, Yusuke Okamura, Yermek Nigmet, Hirofumi Hirao, Toyonari Kubota, Osamu Inamoto, Jiro Kusakabe, Toru Goto, Tetsuya Tajima, Junichi Yoshikawa, Hirokazu Tanaka, Tatsuaki Tsuruyama, Rene H. Tolba, Shinji Uemoto – 18 August 2018 – Cold storage (CS) remains the gold standard for organ preservation worldwide, although it is inevitably associated with ischemia/reperfusion injury (IRI). Molecular hydrogen (H2) is well known to have antioxidative properties.

Donor‐Specific Antibodies in Pediatric Intestinal and Multivisceral Transplantation: The Role of Liver and Human Leukocyte Antigen Mismatching

Paloma Talayero, Esther Ramos Boluda, Elena Gómez Massa, María José Castro Panete, Gerardo Prieto Bozano, Francisco Hernández Oliveros, Manuel López Santamaría, Jorge Calvo Pulido, Estela Paz‐Artal, Esther Mancebo – 16 August 2018 – Rejection is one of the most important drawbacks for graft and patient survival in intestinal and multivisceral transplantation.

Flare of Autoimmune Hepatitis Causing Acute on Chronic Liver Failure: Diagnosis and Response to Corticosteroid Therapy

Lovkesh Anand, Ashok Choudhury, Chhagan Bihari, Barjesh C. Sharma, Manoj Kumar, Rakhi Maiwall, Soek Siam Tan, Samir R. Shah, Saeed Hamid, Amna S. Butt, Wasim Jafri, Yogesh K. Chawla, Sunil Taneja, Ajay Duseja, Radha K. Dhiman, Mamun Al Mahtab, Hasmik Ghazinyan, Zhongping Duan, Yu Chen, Akash Shukla, Jinhua Hu, Zaigham Abbas, Sombat Treeprasertsuk, Laurentius A. Lesmana, Cosmas R Lesmana, Jose D. Sollano, Gian Carpio, Manoj K. Sahu, Guresh Kumar, Shiv K.

Macrophage‐Specific Hypoxia‐Inducible Factor‐1α Contributes to Impaired Autophagic Flux in Nonalcoholic Steatohepatitis

Xiaojing Wang, Marcelle de Carvalho Ribeiro, Arvin Iracheta‐Vellve, Patrick Lowe, Aditya Ambade, Abhishek Satishchandran, Terence Bukong, Donna Catalano, Karen Kodys, Gyongyi Szabo – 13 August 2018 – Inflammatory cell activation drives diverse cellular programming during hepatic diseases. Hypoxia‐inducible factors (HIFs) have recently been identified as important regulators of immunity and inflammation.

Genetics Meets Therapy? Exome‐wide Association Study Reveals a Loss‐of‐Function Variant in 17‐Beta‐Hydroxysteroid Dehydrogenase 13 That Protects Patients From Liver Damage and Nonalcoholic Fatty Liver Disease Progression

Bile Microinfarcts in Cholestasis Are Initiated by Rupture of the Apical Hepatocyte Membrane and Cause Shunting of Bile to Sinusoidal Blood

Ahmed Ghallab, Ute Hofmann, Selahaddin Sezgin, Nachiket Vartak, Reham Hassan, Ayham Zaza, Patricio Godoy, Kai Markus Schneider, Georgia Guenther, Yasser A. Ahmed, Aya A. Abbas, Verena Keitel, Lars Kuepfer, Steven Dooley, Frank Lammert, Christian Trautwein, Michael Spiteller, Dirk Drasdo, Alan F. Hofmann, Peter L.M. Jansen, Jan G. Hengstler, Raymond Reif – 13 August 2018 – Bile duct ligation (BDL) is an experimental procedure that mimics obstructive cholestatic disease.

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