A Validated Score Predicts Acute Kidney Injury and Survival in Patients With Alcoholic Hepatitis

Ravi Sujan, Monica Cruz‐Lemini, Jose Altamirano, Douglas A. Simonetto, Rakhi Maiwall, Page Axley, Taylor Richardson, Vivek Desai, Joaquin Cabezas, Victor Vargas, Patrick S. Kamath, Vijay H. Shah, Shiv K. Sarin, Ramon Bataller, Ashwani K. Singal – 28 August 2018 – Identifying patients at high risk for acute kidney injury (AKI) during hospitalization among patients admitted with severe alcoholic hepatitis (AH) is an unmet clinical need. We performed a multicentric prospective cohort study using data from 4 different cohorts on well‐characterized patients hospitalized with severe AH.

Preventing Hepatitis B Reactivation During Anti‐CD20 Antibody Treatment in the Veterans Health Administration

A. Jasmine Bullard, Francesca E. Cunningham, Bryan D. Volpp, Elliott Lowy, Lauren A. Beste, Bernadette B. Heron, Mark Geraci, Julia M. Hammond, Kourtney LaPlant, Elise A. Stave, Marsha J. Turner, Meghan C. O’Leary, Michael J. Kelley, Christine M. Hunt – 28 August 2018 – Hepatitis B virus (HBV) reactivation may occur with high risk immunosuppression, such as anti‐cluster of differentiation (CD)20 antibodies (Abs). Appropriate HBV prophylaxis during anti‐CD20 Ab therapy averts hepatitis, chemotherapy disruption, and death.

Advanced Hepatocellular Carcinoma Tumor Stage at Diagnosis in the 1945‐1965 Birth Cohort Reflects Poor Use of Hepatocellular Carcinoma Screening

Ann Robinson, Hesam Tavakoli, Benny Liu, Taft Bhuket, Robert J. Wong – 28 August 2018 – Individuals from the 1945‐1965 birth cohort account for the majority of hepatocellular carcinoma (HCC) cases in the United States. Understanding trends in HCC among this birth cohort is vital given the increasing burden of chronic liver disease among this group. We retrospectively evaluated trends and disparities in HCC tumor stage at the time of diagnosis among the 1945‐1965 birth cohort in the United States using the Surveillance, Epidemiology, and End Results (SEER) cancer registry.

Splenectomy as Flow Modulation Strategy and Risk Factors of De Novo Portal Vein Thrombosis in Adult‐to‐Adult Living Donor Liver Transplantation

Ivan Linares, Nicolas Goldaracena, Roizar Rosales, Luis De la Maza, Moritz Kaths, Dagmar Kollmann, Juan Echeverri, Nazia Selzner, Stuart A. McCluskey, Gonzalo Sapisochin, Leslie B. Lilly, Paul Greig, Mamatha Bhat, Anand Ghanekar, Mark Cattral, Ian McGilvray, David Grant, Markus Selzner – 26 August 2018 – Portal vein thrombosis (PVT) is a severe complication after liver transplantation that can result in increased morbidity and mortality. Few data are available regarding risk factors, classification, and treatment of PVT after living donor liver transplantation (LDLT).

Onset of Donor Warm Ischemia Time in Donation After Circulatory Death Liver Transplantation: Hypotension or Hypoxia?

Marit Kalisvaart, Jubi E. Haan, Wojciech G. Polak, Jan N. M. IJzermans, Diederik Gommers, Herold J. Metselaar, Jeroen Jonge – 24 August 2018 – The aim of this study was to investigate the impact of hypoxia and hypotension during the agonal phase of donor warm ischemia time (DWIT) on hepatic ischemia/reperfusion injury (IRI) and complications in donation after circulatory death (DCD) liver transplantation. A retrospective single‐center study of 93 DCD liver transplants (Maastricht type III) was performed.

Subscribe to