Normothermic machine perfusion reduces bile duct injury and improves biliary epithelial function in rat donor livers
Sanna op den Dries, Negin Karimian, Andrie C. Westerkamp, Michael E. Sutton, Michiel Kuipers, Janneke Wiersema‐Buist, Petra J. Ottens, Jeroen Kuipers, Ben N. Giepmans, Henri G. D. Leuvenink, Ton Lisman, Robert J. Porte – 6 March 2016 – Bile duct injury may occur during liver procurement and transplantation, especially in livers from donation after circulatory death (DCD) donors. Normothermic machine perfusion (NMP) has been shown to reduce hepatic injury compared to static cold storage (SCS). However, it is unknown whether NMP provides better preservation of bile ducts.