Hashem B. El‐Serag, Fasiha Kanwal, Peter Richardson, Jennifer Kramer – 4 March 2016 – The long‐term prognosis in terms of risk or predictors of developing hepatocellular carcinoma (HCC) among patients with sustained virological response (SVR) remains unclear. We conducted a retrospective cohort study using data from the Veterans Affairs VA hepatitis C virus (HCV) Clinical Case Registry in patients with positive HCV RNA between October 1999 and August 2009 and follow‐up through December 2010.

3 March 2016

Jonggi Choi, Hassan M. Ghoz, Thoetchai Peeraphatdit, Esha Baichoo, Benyam D. Addissie, William S. Harmsen, Terry M. Therneau, Janet E. Olson, Roongruedee Chaiteerakij, Lewis R. Roberts – 3 March 2016 – Whether aspirin use is protective against cholangiocarcinoma (CCA) remains unclear. We determined the association between aspirin use and other risk factors for each CCA subtype individually. In a hospital‐based case‐control study, 2395 CCA cases (1169 intrahepatic, 995 perihilar, and 231 distal) seen at the Mayo Clinic, Rochester, MN, from 2000 through 2014 were enrolled.

3 March 2016

Pranoti Mandrekar, Ramon Bataller, Hidekazu Tsukamoto, Bin Gao – 3 March 2016 – Alcoholic liver disease is a leading cause of liver‐related mortality worldwide. In contrast to recent advances in therapeutic strategies for patients with viral hepatitis, there is a significant lack of novel therapeutic options for patients with alcoholic liver disease. In particular, there is an urgent need to focus our efforts on effective therapeutic interventions for alcoholic hepatitis (AH), the most severe form of alcoholic liver disease.

Elliot B. Tapper – 3 March 2016

Angels Escorsell, Jaime Bosch – 3 March 2016

Chenguang Dai, Lili Zhao, Li Liu, Xiang Wang, Min Wang, Zhining Fan – 3 March 2016

Marcus R. Pereira, Anne‐Catrin Uhlemann – 2 March 2016

Abhishek Chauhan, David H. Adams, Steve P. Watson, Patricia F. Lalor – 2 March 2016 – Growing lines of evidence recognize that platelets play a central role in liver homeostasis and pathobiology. Platelets have important roles at every stage during the continuum of liver injury and healing. These cells contribute to the initiation of liver inflammation by promoting leukocyte recruitment through sinusoidal endothelium.