Andrew S. Chu, Kapil B. Chopra, David H. Perlmutter – 6 March 2016 – The classical form of alpha‐1‐antitrypsin deficiency (A1ATD) is known to cause liver disease in children and adults, but there is relatively little information about the risk of severe, progressive liver disease and the need for liver transplantation.
Ana Cristina Aoun Tannuri, Gilda Porta, Irene Kazue Miura, Maria Merces Santos, Daniel de Albuquerque Rangel Moreira, Nathassia Mancebo Avila de Rezende, Helena Thie Miyatani, Uenis Tannuri – 6 March 2016 – Acute liver failure (ALF) in children is a life‐threatening condition that often leads to urgent liver transplantation (LT). The aim of the present investigation was to describe the experience in Brazil in treating pediatric ALF, with an emphasis on the role of living donor liver transplantation (LDLT) in treating this condition.
Sarah A. Taylor, Peter F. Whitington – 6 March 2016 – Neonatal acute liver failure (NALF) is a rare disease about which there is little published data; however, NALF is an extremely important condition as it is distinct from acute liver failure seen in older children and adults. First, unlike acute liver failure in older patients, NALF can be diagnosed in an infant with cirrhosis. This is due to the fetal‐neonatal continuum of liver disease, or the principle that neonatal liver failure may be the result of a liver disease that began in utero.
Sanna op den Dries, Negin Karimian, Andrie C. Westerkamp, Michael E. Sutton, Michiel Kuipers, Janneke Wiersema‐Buist, Petra J. Ottens, Jeroen Kuipers, Ben N. Giepmans, Henri G. D. Leuvenink, Ton Lisman, Robert J. Porte – 6 March 2016 – Bile duct injury may occur during liver procurement and transplantation, especially in livers from donation after circulatory death (DCD) donors. Normothermic machine perfusion (NMP) has been shown to reduce hepatic injury compared to static cold storage (SCS). However, it is unknown whether NMP provides better preservation of bile ducts.
Kai‐Henrik Peiffer, Lisa Sommer, Stefan Zeuzem, Christoph Sarrazin – 4 March 2016
Juan G. Abraldes, Kelly W. Burak – 4 March 2016
James Hamilton, Svetlana Lutsenko – 4 March 2016
Hashem B. El‐Serag, Fasiha Kanwal, Peter Richardson, Jennifer Kramer – 4 March 2016 – The long‐term prognosis in terms of risk or predictors of developing hepatocellular carcinoma (HCC) among patients with sustained virological response (SVR) remains unclear. We conducted a retrospective cohort study using data from the Veterans Affairs VA hepatitis C virus (HCV) Clinical Case Registry in patients with positive HCV RNA between October 1999 and August 2009 and follow‐up through December 2010.
Chiara Gabbi, Marco Bertolotti – 4 March 2016
Vincent Pedergnana, David Smith, STOP‐HCV Consortium, Paul Klenerman, Eleanor Barnes, Chris C. A. Spencer, M. Azim Ansari – 4 March 2016