CD14 is associated with biliary stricture formation
Kilian Friedrich, Mark Smit, Maik Brune, Thomas Giese, Christian Rupp, Andreas Wannhoff, Petra Kloeters, Yvonne Leopold, Gerald Ulrich Denk, Karl Heinz Weiss, Wolfgang Stremmel, Peter Sauer, Simon Hohenester, Peter Schirmacher, Peter Schemmer, Daniel Nils Gotthardt – 11 March 2016 – The pathogenesis of intrahepatic biliary stricture formation in patients with primary sclerosing cholangitis (PSC) or after liver transplantation (LTx) remains elusive. CD14 receptor signaling is a key mediator of the innate immune system; its common genetic variant is associated with alcoholic liver disease.