Role of patient factors, preferences, and distrust in health care and access to liver transplantation and organ donation

Julius M. Wilder, Omobonike O. Oloruntoba, Andrew J. Muir, Cynthia A. Moylan – 30 March 2016 – Despite major improvements in access to liver transplantation (LT), disparities remain. Little is known about how distrust in medical care, patient preferences, and the origins shaping those preferences contribute to differences surrounding access. We performed a single‐center, cross‐sectional survey of adults with end‐stage liver disease and compared responses between LT listed and nonlisted patients as well as by race.

Liver transplantation in Australia and New Zealand

Geoffrey W. McCaughan, Stephen R. Munn – 30 March 2016 – Liver transplantation (LT) in Australia and New Zealand began in 1985. Over this time until December 2014, LT took place in 3700 adults and 800 children. LT is regulated with 1 unit, supported by the government, per state or region. Currently approximately 270 transplants take place per year. Organ donation rates are moderate in Australia (17 per 1 million of population) but very low in New Zealand (11 per 1 million of population). All the units share organ donors for fulminant hepatic failure cases (status 1).

Gut microbiota profiling of pediatric nonalcoholic fatty liver disease and obese patients unveiled by an integrated meta‐omics‐based approach

Federica Del Chierico, Valerio Nobili, Pamela Vernocchi, Alessandra Russo, Cristiano De Stefanis, Daniela Gnani, Cesare Furlanello, Alessandro Zandonà, Paola Paci, Giorgio Capuani, Bruno Dallapiccola, Alfredo Miccheli, Anna Alisi, Lorenza Putignani – 29 March 2016 – There is evidence that nonalcoholic fatty liver disease (NAFLD) is affected by gut microbiota. Therefore, we investigated its modifications in pediatric NAFLD patients using targeted metagenomics and metabolomics.

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