Liver Capsule: FXR agonists against liver disease
Claudia D. Fuchs, Peter Schwabl, Thomas Reiberger, Michael Trauner – 16 September 2016
Rubicon inhibits autophagy and accelerates hepatocyte apoptosis and lipid accumulation in nonalcoholic fatty liver disease in mice
Satoshi Tanaka, Hayato Hikita, Tomohide Tatsumi, Ryotaro Sakamori, Yasutoshi Nozaki, Sadatsugu Sakane, Yuto Shiode, Tasuku Nakabori, Yoshinobu Saito, Naoki Hiramatsu, Keisuke Tabata, Tsuyoshi Kawabata, Maho Hamasaki, Hidetoshi Eguchi, Hiroaki Nagano, Tamotsu Yoshimori, Tetsuo Takehara – 16 September 2016 – Nonalcoholic fatty liver disease (NAFLD) is the most prevalent liver disease worldwide. It encompasses a spectrum ranging from simple steatosis to fatty liver with hepatocellular injury, termed nonalcoholic steatohepatitis.
Emerging complexities with hepatitis C virus direct‐acting antiviral regimens: Less is still Way more
Lucas A. Hill, David L. Wyles – 16 September 2016
Emerging complexities with hepatitis C virus direct‐acting antiviral regimens: Less is still Way more
Lucas A. Hill, David L. Wyles – 16 September 2016
Liver Capsule: FXR agonists against liver disease
Claudia D. Fuchs, Peter Schwabl, Thomas Reiberger, Michael Trauner – 16 September 2016
Silencing sirtuins: A novel way to thwart reperfusion injury?
Pieter Borger, Pierre‐Alain Clavien – 15 September 2016
Extracellular vesicles in liver pathobiology: Small particles with big impact
Petra Hirsova, Samar H. Ibrahim, Vikas K. Verma, Leslie A. Morton, Vijay H. Shah, Nicholas F. LaRusso, Gregory J. Gores, Harmeet Malhi – 15 September 2016 – Extracellular vesicles (EVs) are nanometer‐sized, membrane‐bound vesicles released by cells into the extracellular milieu. EVs are now recognized to play a critical role in cell‐to‐cell communication. EVs contain important cargo in the form of proteins, lipids, and nucleic acids and serve as vectors for delivering this cargo from donor to acceptor or target cell.
The cystic fibrosis transmembrane conductance regulator controls biliary epithelial inflammation and permeability by regulating Src tyrosine kinase activity
Romina Fiorotto, Ambra Villani, Antonis Kourtidis, Roberto Scirpo, Mariangela Amenduni, Peter J. Geibel, Massimiliano Cadamuro, Carlo Spirli, Panos Z. Anastasiadis, Mario Strazzabosco – 15 September 2016 – In the liver, the cystic fibrosis (CF) transmembrane conductance regulator (CFTR) regulates bile secretion and other functions at the apical membrane of biliary epithelial cells (i.e., cholangiocytes). CF‐related liver disease is a major cause of death in patients with CF.
Biliary adenofibroma: A rare hepatic lesion with malignant features
Paul Kaminsky, Joshua Preiss, Eizaburo Sasatomi, David A. Gerber – 15 September 2016
Characterization of the Specificity, Functionality, and Durability of Host T‐Cell Responses Against the Full‐Length Hepatitis E Virus
Anthony Brown, John S. Halliday, Leo Swadling, Richie G. Madden, Richard Bendall, Jeremy G. Hunter, James Maggs, Peter Simmonds, Donald B. Smith, Louisa Vine, Cara McLaughlin, Jane Collier, David Bonsall, Katie Jeffery, Susanna Dunachie, Paul Klenerman, Jacques Izopet, Nassim Kamar, Harry R. Dalton, Eleanor Barnes – 15 September 2016 – The interplay between host antiviral immunity and immunopathology during hepatitis E virus (HEV) infection determines important clinical outcomes.