Carla Venturi, Raymond Reding, Jorge Abarca Quinones, Etienne Sokal, Jacques Rahier, Javier Bueno, Christine Sempoux – 6 February 2016 – Activated hepatic stellate cells (HSCs) are the main collagen‐producing cells in liver fibrogenesis. With the purpose of analyzing their presence and relevance in predicting liver allograft fibrosis development, 162 liver biopsies of 54 pediatric liver transplantation (LT) recipients were assessed at 6 months, 3 years, and 7 years after LT.

Daisuke Ito, Nobuhisa Akamatsu, Akihiko Ichida, Junichi Kaneko, Junichi Arita, Kiyoshi Hasegawa, Yoshihiro Sakamoto, Norihiro Kokudo – 6 February 2016

Amy G. Feldman, Katie Neighbors, Shubhra Mukherjee, Melanie Rak, James W. Varni, Estella M. Alonso – 6 February 2016 – The purpose of this article is to investigate the spectrum of physical function of pediatric liver transplantation (LT) recipients 12‐24 months after LT. Review data were collected through the functional outcomes group, an ancillary study of the Studies of Pediatric Liver Transplantation registry. Patients were eligible if they had survived LT by 12‐24 months.

Sung‐Hoon Kim, Young‐Jin Moon, Sooho Lee, Sung‐Moon Jeong, Jun‐Gol Song, Gyu‐Sam Hwang – 6 February 2016 – Hemodynamic perturbation during hepatic graft reperfusion in patients undergoing liver transplantation (LT) is challenging and is frequently accompanied by bradyarrhythmia and even asystole. However, detailed data on electrocardiographic (ECG) changes during reperfusion are almost nonexistent, although the correct diagnosis by record is important for the treatment. We aimed to identify ECG rhythm disturbances during graft reperfusion and to investigate risk factors and outcomes.

Eduardo Vilar‐Gomez, Ali Yasells‐Garcia, Yadina Martinez‐Perez, Luis Calzadilla‐Bertot, Ana Torres‐Gonzalez, Bienvenido Gra‐Oramas, Licet Gonzalez‐Fabian, Oscar Villa‐Jimenez, Scott L. Friedman, Moises Diago, Manuel Romero‐Gomez – 5 February 2016 – Liver biopsy is the gold standard method to assess nonalcoholic steatohepatitis (NASH) resolution after therapeutic interventions. We developed and validated a simple and noninvasive scoring system to predict NASH resolution without fibrosis worsening after 1 year of lifestyle intervention.

Tsunekazu Oikawa – 5 February 2016 – Liver and biliary tract cancers are highly aggressive, are heterogeneous in their phenotypic traits, and result in clinical outcomes that are difficult to manage. Cancers have subpopulations of cells termed “cancer stem cells” (CSCs) that share common intrinsic signaling pathways for self‐renewal and differentiation with normal stem cells. These CSCs likely have the potential to evolve over time and to give rise to new genetically and functionally diverse subclones by accumulating genetic mutations.

Mark H. Kuniholm, Kenrad E. Nelson – 4 February 2016

Jonel Trebicka, Robert Schierwagen – 4 February 2016

Birendra Prasad Gupta, Ananta Shrestha, Anurag Adhikari, Thupten Kelsang Lama, Binaya Sapkota – 4 February 2016

Christine E. McLaren, James C. Barton, V. Nathan Subramaniam, Grant A. Ramm, Pradyumna D. Phatak, Mary J. Emond, Lyle C. Gurrin, Paul C. Adams, Lawrie W. Powell, Gregory J. Anderson, Gordon D. McLaren – 4 February 2016