GNPAT variant is associated with iron phenotype in healthy Taiwanese women: A population without the HFE C282Y mutation
Shu‐Chen Hsiao, Chien‐Te Lee, Sung‐Nan Pei – 4 February 2016
Protein tyrosine phosphatase 1B dephosphorylates PITX1 and regulates p120RasGAP in hepatocellular carcinoma
Wei‐Tien Tai, Yao‐Li Chen, Pei‐Yi Chu, Li‐Ju Chen, Man‐Hsin Hung, Chung‐Wai Shiau, Jui‐Wen Huang, Ming‐Hsien Tsai, Kuen‐Feng Chen – 3 February 2016 – The effective therapeutic targets for hepatocellular carcinoma remain limited. Pituitary homeobox 1 (PITX1) functions as a tumor suppressor in hepatocarcinogenesis by regulating the expression level of Ras guanosine triphosphatase‐activating protein. Here, we report that protein tyrosine phosphatases 1B (PTP1B) directly dephosphorylated PITX1 at Y160, Y175, and Y179 to further weaken the protein stability of PITX.
A low‐cost, user‐friendly electroencephalographic recording system for the assessment of hepatic encephalopathy
Sami Schiff, Mariella Casa, Valeria Di Caro, Daniele Aprile, Giuseppe Spinelli, Michele De Rui, Paolo Angeli, Piero Amodio, Sara Montagnese – 2 February 2016 – Electroencephalography (EEG) is useful to objectively diagnose/grade hepatic encephalopathy (HE) across its spectrum of severity. However, it requires expensive equipment, and hepatogastroenterologists are generally unfamiliar with its acquisition/interpretation.
Empiric treatment of nosocomial spontaneous bacterial peritonitis: One size does not fit all
Michael G. Ison – 2 February 2016
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David Hervás, Agustín Lahoz – 29 January 2016
Evaluation and management of insomnia, muscle cramps, fatigue, and itching in cirrhotic patients
Christopher Moore – 29 January 2016
Nutrition, fluid, and electrolytes in chronic liver disease
Miguel A. Lalama, Yasser Saloum – 29 January 2016
Silymarin in the treatment of liver diseases: What is the clinical evidence?
Peter Ferenci – 29 January 2016
Integrating daclatasvir into hepatitis c therapy
Omobonike Oloruntoba, Andrew J. Muir – 29 January 2016
Bundled strategies against infection after liver transplantation: Lessons from multidrug‐resistant Pseudomonas aeruginosa
Asahi Sato, Toshimi Kaido, Taku Iida, Shintaro Yagi, Koichiro Hata, Hideaki Okajima, Shunji Takakura, Satoshi Ichiyama, Shinji Uemoto – 29 January 2016 – Infection is a life‐threatening complication after liver transplantation (LT). A recent outbreak of multidrug‐resistant Pseudomonas aeruginosa triggered changes in our infection control measures. This study investigated the usefulness of our bundled interventions against postoperative infection after LT.