Ling Li, David Masica, Masaharu Ishida, Ciprian Tomuleasa, Sho Umegaki, Anthony N. Kalloo, Christos Georgiades, Vikesh K. Singh, Mouen Khashab, Stuart Amateau, Zhiping Li, Patrick Okolo, Anne‐Marie Lennon, Payal Saxena, Jean‐Francois Geschwind, Todd Schlachter, Kelvin Hong, Timothy M. Pawlik, Marcia Canto, Joanna Law, Reem Sharaiha, Clifford R. Weiss, Paul Thuluvath, Michael Goggins, Eun Ji Shin, Haoran Peng, Vivek Kumbhari, Susan Hutfless, Liya Zhou, Esteban Mezey, Stephen J. Meltzer, Rachel Karchin, Florin M.

Kenji Takahashi, Irene Yan, Hiroaki Haga, Tushar Patel – 3 February 2014 – The identification of the presence of large RNA transcripts that do not code for proteins but that may have biological functions has provided an important new perspective in gene regulation. These long noncoding RNAs (lncRNAs) are being increasingly recognized to contribute to many biological processes through diverse mechanisms. The roles of these emerging genes are being recognized across kingdoms.

Rita R. Alloway, Devin E. Eckhoff, W. Kenneth Washburn, Lewis W. Teperman – 3 February 2014 – LCP‐Tacro is an extended‐release formulation of tacrolimus designed for once‐daily dosing. Studies in renal transplantation demonstrate greater bioavailability with similar safety and efficacy vs. twice‐daily tacrolimus capsules.

Neil Mehta, Jennifer L. Dodge, John Paul Roberts, Ryutaro Hirose, Francis Y. Yao – 3 February 2014

3 February 2014

Jamak Modaresi Esfeh, Ibrahim A. Hanouneh, Christine E. Koval, Christopher Kovacs, Deepan S. Dalal, Kianoush Ansari‐Gilani, Bradley D. Confer, Bijan Eghtesad, Nizar N. Zein, K. V. Narayanan Menon – 3 February 2014 – Bacterial and fungal infections are major causes of morbidity and mortality after liver transplantation (LT). The role of intestinal decontamination in the prevention of post‐LT infections is controversial. Rifaximin is widely used for the treatment of hepatic encephalopathy. The effect of rifaximin on post‐LT infections is unknown.

Manlio Vinciguerra – 3 February 2014

Ghassan K. Abou-Alfa – 3 February 2014

Michael D. Kluger, Karim J. Halazun, Ryan T. Barroso, Alyson N. Fox, Sonja K. Olsen, David C. Madoff, Abby B. Siegel, Joshua L. Weintraub, Jonathan Sussman, Robert S. Brown, Daniel Cherqui, Jean C. Emond – 3 February 2014 – There is conflicting literature regarding the superiority of transarterial chemoembolization (TACE) versus bland transarterial embolization (TAE), and this has not been well studied before transplantation. Twenty‐five TAE patients were matched in a 1:2 ratio with TACE patients by the initial radiographic tumor size and number in a retrospective, case‐controlled study.

Hyo‐Jung Kwon, Young‐Suk Won, Ogyi Park, Binxia Chang, Michael J. Duryee, Geoffrey E. Thiele, Akiko Matsumoto, Surendra Singh, Mohamed A. Abdelmegeed, Byoung‐Joon Song, Toshihiro Kawamoto, Vasilis Vasiliou, Geoffrey M. Thiele, Bin Gao – 3 February 2014 – Aldehyde dehydrogenase 2 (ALDH2) is the major enzyme that metabolizes acetaldehyde produced from alcohol metabolism. Approximately 40‐50% of East Asians carry an inactive ALDH2 gene and exhibit acetaldehyde accumulation after alcohol consumption.