Justification for routine intensive care after liver transplantation
Michael Ramsay – 10 September 2013
Hepatic artery thrombosis: Conservative management or retransplantation?
Nigel D. Heaton – 10 September 2013
Systematic investigation of elevated transaminases during the third posttransplant month
Michael P. Curry – 10 September 2013
How important is acute cellular rejection?
Michael R. Charlton – 10 September 2013
Forkhead box Q1 promotes hepatocellular carcinoma metastasis by transactivating ZEB2 and VersicanV1 expression
Limin Xia, Wenjie Huang, Dean Tian, Lin Zhang, Xingshun Qi, Zhangqian Chen, Xin Shang, Yongzhan Nie, Kaichun Wu – 5 September 2013 – Forkhead box Q1 (FoxQ1) is a master regulator of tumor metastasis. However, the molecular mechanism of FoxQ1 in regulating hepatocellular carcinoma (HCC) metastasis remains unknown. Here we report a novel function for FoxQ1 in modifying the tumor microenvironment to promote HCC metastasis. FoxQ1 expression was an independent and significant risk factor for the recurrence and survival in two independent cohorts totaling 1,002 HCC patients.
Painting the liver with lasers: The future of liver histology?
Diren Beyoğlu, Jeffrey R. Idle – 5 September 2013
Critical interaction between E1 and E2 glycoproteins determines binding and fusion properties of hepatitis C virus during cell entry
Florian Douam, Viet Loan Dao Thi, Guillemette Maurin, Judith Fresquet, Dimitri Mompelat, Mirjam B. Zeisel, Thomas F. Baumert, François‐Loïc Cosset, Dimitri Lavillette – 4 September 2013 – Hepatitis C virus (HCV) envelope glycoproteins E1 and E2 are important mediators for productive cell entry. However, knowledge about their structure, intra‐ or intermolecular dialogs, and conformational changes is scarce, limiting the design of therapeutic strategies targeting E1E2.
Never forget aceruloplasminemia in case of highly suggestive Wilson's disease score
Marjon Kerkhof, Pieter Honkoop – 3 September 2013
c‐Myc‐mediated epigenetic silencing of MicroRNA‐101 contributes to dysregulation of multiple pathways in hepatocellular carcinoma
Lei Wang, Xiang Zhang, Lin‐Tao Jia, Si‐Jun Hu, Jing Zhao, Jian‐Dong Yang, Wei‐Hong Wen, Zhe Wang, Tao Wang, Jun Zhao, Rui‐An Wang, Yan‐Ling Meng, Yong‐Zhan Nie, Ke‐Feng Dou, Si‐Yi Chen, Li‐Bo Yao, Dai‐Ming Fan, Rui Zhang, An‐Gang Yang – 3 September 2013 – The MYC oncogene is overexpressed in hepatocellular carcinoma (HCC) and has been associated with widespread microRNA (miRNA) repression; however, the underlying mechanisms are largely unknown.
Global alterations of DNA methylation in cholangiocarcinoma target the Wnt signaling pathway
Benjamin Goeppert, Carolin Konermann, Christopher Roman Schmidt, Olga Bogatyrova, Lea Geiselhart, Christina Ernst, Lei Gu, Natalia Becker, Manuela Zucknick, Arianeb Mehrabi, Mohammadreza Hafezi, Frederick Klauschen, Albrecht Stenzinger, Arne Warth, Kai Breuhahn, Marcus Renner, Wilko Weichert, Peter Schirmacher, Christoph Plass, Dieter Weichenhan – 3 September 2013 – The molecular mechanisms underlying the genesis of cholangiocarcinomas (CCs) are poorly understood.