Type‐1 hepatorenal syndrome associated with infections in cirrhosis: Natural history, outcome of kidney function, and survival

Rogelio Barreto, Claudia Fagundes, Mónica Guevara, Elsa Solà, Gustavo Pereira, Ezequiel Rodríguez, Isabel Graupera, Marta Martín‐Llahí, Xavier Ariza, Andrés Cárdenas, Javier Fernández, Juan Rodés, Vicente Arroyo, Pere Ginès – 19 August 2013 – Type‐1 hepatorenal syndrome (HRS) is a common complication of bacterial infections in cirrhosis, but its natural history remains undefined. To assess the outcome of kidney function and survival of patients with type‐1 HRS associated with infections, 70 patients diagnosed during a 6‐year period were evaluated prospectively.

Chemokine receptor CCR6‐dependent accumulation of γδ T cells in injured liver restricts hepatic inflammation and fibrosis

Linda Hammerich, Jörg M. Bangen, Olivier Govaere, Henning W. Zimmermann, Nikolaus Gassler, Sebastian Huss, Christian Liedtke, Immo Prinz, Sergio A. Lira, Tom Luedde, Tania Roskams, Christian Trautwein, Felix Heymann, Frank Tacke – 19 August 2013 – Chronic liver injury promotes hepatic inflammation, representing a prerequisite for organ fibrosis. We hypothesized a contribution of chemokine receptor CCR6 and its ligand, CCL20, which may regulate migration of T‐helper (Th)17, regulatory, and gamma‐delta (γδ) T cells.

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