New highlights for relaxin
Klaas Poelstra – 28 August 2013
Klaas Poelstra – 28 August 2013
David S. Goldberg, George Makar, Therese Bittermann, Benjamin French – 27 August 2013 – The Model for End‐Stage Liver Disease (MELD) score is an imperfect prognosticator of waitlist dropout, so transplant centers may apply for exception points to increase a waitlist candidate's priority on the waitlist. Exception applications are categorized as recognized exceptional diagnoses (REDs; eg, hepatocellular carcinoma) and non‐REDs (eg, cholangitis). Although prior work has demonstrated regional variation in the use of exceptions, no work has examined the between‐center variability.
Andres Duarte‐Rojo, Vikram Budhraja, Bart J. Veldt, David D. Goldstein, Kymberly D. Watt, Julie K. Heimbach, John G. McHutchison, Hans L. Tillman, John J. Poterucha, Michael R. Charlton – 27 August 2013 – Chronic hepatitis C (CHC)–related cirrhosis is the leading indication for liver transplantation (LT). However, the recurrence of a hepatitis C virus (HCV) infection after transplantation is universal and is associated with worse outcomes.
Mettu Srinivas Reddy, Gomathy Narasimhan, Pradeep Thomas Cherian, Mohamed Rela – 27 August 2013
Abdl‐Rawf Al‐Nowaylati, Benjamin J. S. Al‐Haddad, Rob B. Dorman, Osama A. Alsaied, John R. Lake, Srinath Chinnakotla, Bridget M. Slusarek, Barbara K. Sampson, Sayeed Ikramuddin, Henry Buchwald, Daniel B. Leslie – 27 August 2013 – Few data are available for assessing the outcomes of bariatric surgery for patients who have undergone orthotopic liver transplantation (OLT).
Mariya L. Samoylova, Jennifer L. Dodge, Eric Vittinghoff, Francis Y. Yao, John Paul Roberts – 27 August 2013 – The Organ Procurement and Transplantation Network (OPTN)/United Network for Organ Sharing (UNOS) database is the most comprehensive collection of liver transplantation data, but the quality of these data with respect to hepatocellular carcinoma (HCC) recurrence has not been well assessed.
Seong Chul Kim, Chun‐Ki Kim, David Axe, Aaron Cook, Mikang Lee, Tiangang Li, Nicole Smallwood, John Y.L. Chiang, James P. Hardwick, David D. Moore, Yoon Kwang Lee – 26 August 2013
Tongsen Zheng, Xuehui Hong, Jiabei Wang, Tiemin Pei, Yingjian Liang, Dalong Yin, Ruipeng Song, Xuan Song, Zhaoyang Lu, Shuyi Qi, Jiaren Liu, Boshi Sun, Changming Xie, Shangha Pan, Yuejin Li, Xiaohe Luo, Shuai Li, Xiang Fang, Nishant Bhatta, Hongchi Jiang, Lianxin Liu – 26 August 2013 – Although gankyrin is involved in the tumorigenicity and metastasis of some malignancies, the role of gankyrin in cholangiocarcinoma (CCA) is unclear. In this study we investigated the expression of gankyrin in human CCA tissues and cell lines.
Daniel Seidel, Ira Eickmeier, Anja A. Kühl, Alf Hamann, Christoph Loddenkemper, Eckart Schott – 26 August 2013 – The pathogenesis of primary sclerosing cholangitis (PSC) remains poorly understood. Since PSC predominantly occurs in patients with inflammatory bowel disease, autoimmunity triggered by activated T cells migrating from the gut to the liver is a possible mechanism. We hypothesized that T cells primed in the gut‐associated lymphoid tissue (GALT) by a specific antigen migrate to the liver and cause cholangitis when they recognize the same antigen on cholangiocytes.
Andrea Lisotti, Francesco Azzaroli, Federica Buonfiglioli, Marco Montagnani, Paolo Cecinato, Laura Turco, Claudio Calvanese, Patrizia Simoni, Massimo Guardigli, Rosario Arena, Alessandro Cucchetti, Antonio Colecchia, Davide Festi, Rita Golfieri, Giuseppe Mazzella – 26 August 2013 – Noninvasive markers would be useful for the assessment of portal hypertension (PH) and esophageal varices (EV) in patients with cirrhosis.