Promotion of diet‐induced obesity and metabolic syndromes by BID is associated with gut microbiota

Shengmin Yan, Jun Zhou, Hao Zhang, Zhen Lin, Bilon Khambu, Gang Liu, Michelle Ma, Xiaoyun Chen, Naga Chalasani, Xiao‐Ming Yin – 14 November 2022 – A growing body of evidence has indicated an expanding functional network of B‐cell lymphoma 2 (BCL‐2) family proteins beyond regulation of cell death and survival. Here, we examined the role and mechanisms of BH3 interacting‐domain death agonist (BID), a pro‐death BCL‐2 family member, in the development of diet‐induced metabolic dysfunction.

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