Dysregulation of global circular RNA abundance regulated by spliceosomes predicts prognosis in hepatocellular carcinoma

Lei He, Liman Qiu, Feng Chen, Tingting Chen, Fang Peng, Zhenli Li, Xiuqing Dong, Zhixiong Cai, Yuanchang Fang, Hengkai Chen, Geng Chen, Xiaolong Liu – 7 November 2022 – CircRNAs have been reported to play crucial roles in tumor progression and recurrence, showing potential as biomarkers in cancer. However, the global abundance of circRNA and their involvement in hepatocellular carcinoma (HCC) development have not been fully explored.

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