Sheng‐Hui Lan, Shan‐Ying Wu, Roberto Zuchini, Xi‐Zhang Lin, Ih‐Jen Su, Ting‐Fen Tsai, Yen‐Ju Lin, Cheng‐Tao Wu, Hsiao‐Sheng Liu – 1 August 2013 – In hepatocellular carcinoma (HCC), dysregulated expression of microRNA‐224 (miR‐224) and impaired autophagy have been reported separately. However, the relationship between them has not been explored. In this study we determined that autophagy is down‐regulated and inversely correlated with miR‐224 expression in hepatitis B virus (HBV)‐associated HCC patient specimens. These results were confirmed in liver tumors of HBV X gene transgenic mice.

Kris P. Croome, William Wall, Natasha Chandok, Gavin Beck, Paul Marotta, Roberto Hernandez‐Alejandro – 1 August 2013 – The impact of ischemia/reperfusion injury in the setting of transplantation for hepatocellular carcinoma (HCC) has not been thoroughly investigated. The present study examined data from the Scientific Registry of Transplant Recipients for all recipients of deceased donor liver transplants performed between January 1, 1995 and October 31, 2011.

Chloé Latour, Léon Kautz, Céline Besson‐Fournier, Marie‐Laure Island, François Canonne‐Hergaux, Olivier Loréal, Tomas Ganz, Hélène Coppin, Marie‐Paule Roth – 1 August 2013 – Gender‐related disparities in the regulation of iron metabolism may contribute to the differences exhibited by men and women in the progression of chronic liver diseases associated with reduced hepcidin expression, e.g., chronic hepatitis C, alcoholic liver disease, or hereditary hemochromatosis. However, their mechanisms remain poorly understood.

Sabrina A. Stratton, Michelle Craig Barton – 1 August 2013

Shaija S. Kutty, Qinghai Peng, David A. Danford, Scott E. Fletcher, Deborah Perry, Geoffrey A. Talmon, Cynthia Scott, John D. Kugler, Kim F. Duncan, Ruben E. Quiros‐Tejeira, Shelby Kutty, the Liver Adult‐Pediatric‐Congenital‐Heart‐Disease Dysfunction Study (LADS) Group – 31 July 2013 – Hepatic dysfunction is a recognized complication after Fontan palliation of congenital heart disease. We sought to quantitatively measure hepatic stiffness and vascular Doppler indices using ultrasound (US) and shear wave elastography (SWE) in a Fontan cohort.

Priya Grewal, Saleem Kamili, David Motamed – 31 July 2013

K. Rajender Reddy, Gregory T. Everson – 31 July 2013

Kenneth E. Sherman, David Thomas, Raymond T. Chung – 31 July 2013 – In the United States, more than 1.1 million individuals are infected with the human immunodeficiency virus (HIV). These patients exhibit a high frequency of coinfections with other hepatotropic viruses and ongoing fibrosis, leading to cirrhosis and liver‐related mortality.

Stephen Casey, Anthony Schelleman, Peter Angus – 31 July 2013

Ser Yee Lee, Michael A. Mooney, Matthew L. Inra, Krishna Juluru, Alyson N. Fox, Sonja K. Olsen, Robert S. Brown, Jean C. Emond, Daniel Cherqui, Michael D. Kluger – 31 July 2013 – Substantial evidence has linked ionizing radiation exposure (RE) to oncogenesis. Patients evaluated for transplantation undergo extensive diagnostic imaging and have increased baseline cancer risk factors. The objective was to examine exposure in a cohort of patients undergoing evaluation and liver transplantation. Radiation exposure from all diagnostic examinations and procedures were retrospectively recorded.