Fast‐tracking and fairness: Getting organ offers quickly to candidates who will accept them
Sommer E. Gentry, Dorry L. Segev – 27 February 2013
Moving toward evidence‐based liver allocation in patients with primary sclerosing cholangitis
Russell H. Wiesner – 27 February 2013
Role of microdialysis catheters in clinical decision making: Bench to bedside?
Michael Ramsay – 27 February 2013
Find it in your heart
Leila Kia, Mary F. Mulcahy, Josh Levitsky – 27 February 2013
Hepatitis C virus NS5B polymerase primes innate immune signaling
Gisa Gerold, Thomas Pietschmann – 21 February 2013
Down the liver sinusoidal endothelial cell (LSEC) hole. Is there a role for lipid rafts in LSEC fenestration?
Juan Rodriguez‐Vita, Manuel Morales‐Ruiz – 21 February 2013
Frequency of the cholesteryl ester storage disease common LIPA E8SJM mutation (c.894G>A) in various racial and ethnic groups
Stuart A. Scott, Benny Liu, Irina Nazarenko, Suparna Martis, Julia Kozlitina, Yao Yang, Charina Ramirez, Yumi Kasai, Tommy Hyatt, Inga Peter, Robert J. Desnick – 19 February 2013 – Cholesteryl ester storage disease (CESD) and Wolman disease are autosomal recessive later‐onset and severe infantile disorders, respectively, which result from the deficient activity of lysosomal acid lipase (LAL). LAL is encoded by LIPA (10q23.31) and the most common mutation associated with CESD is an exon 8 splice junction mutation (c.894G>A; E8SJM), which expresses only ∼3%‐5% of normally spliced LAL.
Jay Donald Ostrow: The yellow giant
Claudio Tiribelli, Libor Vitek, Richard P. Wennberg – 19 February 2013
Reply to Elastin‐based molecular MRI of liver fibrosis
Antonella Pellicoro, John P. Iredale – 19 February 2013
Taurolithocholate‐induced MRP2 retrieval involves MARCKS phosphorylation by protein kinase Cϵ in HUH‐NTCP Cells
Christopher M. Schonhoff, Cynthia R. L. Webster, M. Sawkat Anwer – 19 February 2013 – Taurolithocholate (TLC) acutely inhibits the biliary excretion of multidrug‐resistant associated protein 2 (Mrp2) substrates by inducing Mrp2 retrieval from the canalicular membrane, whereas cyclic adenosine monophosphate (cAMP) increases plasma membrane (PM)–MRP2. The effect of TLC may be mediated via protein kinase Cϵ (PKCϵ). Myristoylated alanine‐rich C kinase substrate (MARCKS) is a membrane‐bound F‐actin crosslinking protein and is phosphorylated by PKCs.