Hepatitis C virus 1b viral factors (core, NS3, and NS5A) and increased risk of hepatocellular carcinoma
Suresh D. Sharma – 7 March 2013
Concordance between sustained virologic response week 12 (SVR12) and SVR24 in genotype 1 hepatitis C virus patients receiving interferon‐free treatment in the SOUND‐C2 study
Stefan Zeuzem, Federico J. Mensa – 7 March 2013
Therapy for lysosomal acid lipase deficiency: Replacing a missing link
Gregory Grabowski – 7 March 2013
Therapy for lysosomal acid lipase deficiency: Replacing a missing link
Gregory Grabowski – 7 March 2013
Impact of primary biliary cirrhosis on perceived quality of life: The UK‐PBC national study
George F. Mells, Greta Pells, Julia L. Newton, Andrew J. Bathgate, Andrew K. Burroughs, Michael A. Heneghan, James M. Neuberger, Darren B. Day, Samantha J. Ducker, Richard N. Sandford, Graeme J. Alexander, David E.J. Jones, UK‐PBC Consortium – 7 March 2013 – Primary biliary cirrhosis (PBC) has a complex clinical phenotype, with debate about the extent and specificity of frequently described systemic symptoms such as fatigue.
Hepatopulmonary syndrome and liver transplantation: Who, when, and where?
Rajasekhar Tanikella, Michael B. Fallon – 7 March 2013
Hepatopulmonary syndrome and liver transplantation: Who, when, and where?
Rajasekhar Tanikella, Michael B. Fallon – 7 March 2013
The nutritional management of hepatic encephalopathy in patients with cirrhosis: International society for hepatic encephalopathy and nitrogen metabolism consensus
Piero Amodio, Chantal Bemeur, Roger Butterworth, Juan Cordoba, Akinobu Kato, Sara Montagnese, Misael Uribe, Hendrik Vilstrup, Marsha Y. Morgan – 7 March 2013 – Nitrogen metabolism plays a major role in the development of hepatic encephalopathy (HE) in patients with cirrhosis. Modulation of this relationship is key to the management of HE, but is not the only nutritional issue that needs to be addressed. The assessment of nutritional status in patients with cirrhosis is problematic.
Interferon regulatory factor 9 protects against hepatic insulin resistance and steatosis in male mice
Xin‐An Wang, Ran Zhang, Dingsheng Jiang, Wei Deng, Shumin Zhang, Shan Deng, Jinfeng Zhong, Tao Wang, Li‐Hua Zhu, Li Yang, Shufen Hong, Sen Guo, Ke Chen, Xiao‐Fei Zhang, Zhigang She, Yingjie Chen, Qinglin Yang, Xiao‐Dong Zhang, Hongliang Li – 7 March 2013 – Obesity is a calorie‐excessive state associated with high risk of diabetes, atherosclerosis, and certain types of tumors. Obesity may induce inflammation and insulin resistance (IR).
MicroRNA‐216a/217‐induced epithelial‐mesenchymal transition targets PTEN and SMAD7 to promote drug resistance and recurrence of liver cancer
Hongping Xia, London Lucien P.J. Ooi, Kam M. Hui – 7 March 2013 – Tumor recurrence and metastases are the major obstacles to improving the prognosis of patients with hepatocellular carcinoma (HCC). To identify novel risk factors associated with HCC recurrence and metastases, we have established a panel of recurrence‐associated microRNAs (miRNAs) by comparing miRNA expression in recurrent and nonrecurrent human HCC tissue samples using microarrays (recurrence is defined as recurrent disease occurring within a 2‐year time point of the original treatment).